Circadian rhythms and circadian rhythm disorders in children and adolescents.

Circadian rhythms and circadian rhythm disorders in children and adolescents.
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DOI:
10.1053/spen.2001.29044
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发表时间:
2001-12-01
影响因子:
2.7
通讯作者:
Mahowald, M
Mahowald, M
中科院分区:
医学4区
文献类型:
--
作者:
Garcia, J;Rosen, G;Mahowald, M

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本文对昼夜节律生理学的临床应用进行了综述,包括对昼夜节律和稳态系统的相互作用以及从先入为主到青春期的昼夜节律系统的成熟进行了详细的研究。重点放在临床评估上,通过病史、睡眠记录以及必要时的动作图和多导睡眠图收集信息。昼夜节律紊乱,包括高级睡眠相综合症,盲童出现的昼夜节律紊乱,睡眠相延迟综合症,以及非24小时睡眠相。文中提供了每个案例的描述。对这些疾病的治疗和干预进行了描述,包括教育、光线治疗、睡眠-觉醒时间表调整的重要性,以及偶尔使用药物,如镇静催眠药和褪黑素。
A clinically applicable review of circadian rhythm physiology is presented, including a detailed examination of the interaction of circadian and homeostatic systems and the maturation of the circadian system from preconception through adolescence. Emphasis is placed on the clinical evaluation gathering information through the history, sleep log, and if necessary, actigraphy and polysomnography. Circadian disorders, including advanced sleep phase syndrome, circadian disorders seen in blind children, delayed sleep phase syndrome, and non-24-hour sleep phase are described. Case descriptions of each are provided. Treatment and interventions for these disorders are described, including the importance of education, light therapy, sleep-wake schedule adjustments, and the occasional use of medications, such as sedative hypnotics and melatonin.