Determinants of Participation in HIV Clinical Trials: The Importance of Patients' Trust in Their Provider
Determinants of Participation in HIV Clinical Trials: The Importance of Patients' Trust in Their Provider
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DOI：
10.1310/hct1002-104
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发表时间：
2009-03-01
影响因子：
--
通讯作者：
Currier, Judith S.
中科院分区：
文献类型：
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作者：
Volkmann, Elizabeth R.;Claiborne, Deon;Currier, Judith S.
Purpose: To investigate the factors that contribute to willingness to participate in HIV clinical trials and to determine the impact of a brief intervention on willingness to participate. Methods: 115 consecutive outpatients receiving HIV primary care participated in this prospective study. Each patient completed a questionnaire about clinical trials and met with a research assistant who discussed the purpose of clinical trials. After the educational intervention, participants completed a second questionnaire and responses from the two surveys were compared. Results: 115 patients were enrolled (56% had previously enrolled in a clinical trial; 50% of whom were currently enrolled in a trial); 92% would consider participating in a future clinical trial. Increased patient trust in the provider was associated with increased willingness to participate in a trial. After the intervention, 94% indicated that they would be willing to be contacted about a clinical trial for which they may be eligible and 85% preferred to be contacted by their primary physician. Conclusions: Patients' trust in their provider may predict willingness to participate in clinical trial. Providing HIV-infected patients and their providers with information about HIV clinical trials at the site where they receive care may increase participation rates in HIV clinical trials.
