The efficacy of permethrin-treated bed nets on child mortality and morbidity in western Kenya I. Development of infrastructure and description of study site
The efficacy of permethrin-treated bed nets on child mortality and morbidity in western Kenya I. Development of infrastructure and description of study site
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DOI：
10.4269/ajtmh.2003.68.3
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发表时间：
2003-04-01
影响因子：
3.3
通讯作者：
Hawley, WA
中科院分区：
文献类型：
--
作者：
Phillips-Howard, PA;Nahlen, BL;Hawley, WA
在撒哈拉以南非洲进行的随机对照试验表明，在疟疾传播率低或高但季节性的地区，用氯菊酯处理过的蚊帐和窗帘可使全因儿童死亡率降低15-33%。本报告描述了在肯尼亚西部一个全年疟疾高传播地区进行的以社区为基础的随机分组对照试验的研究地点。我们概述了进行这项试验所需的人力和物质基础设施的发展，并讨论了在进行这项试验时遇到的一些困难和吸取的教训。
Randomized controlled trials in sub-Saharan Africa have shown that permethrin-treated bed nets and curtains reduce all-cause child mortality by 15-33% in areas with low or high but seasonal malaria transmission. This report describes the study site for a community-based, group-randomized, controlled trial in an area of high and year-round malaria transmission in western Kenya. We outline the development of the human and physical infrastructure required to conduct this trial and discuss some of the difficulties encountered and lessons learned in conducting it.