Changing trends in the clinical features of laryngeal tuberculosis: a report of 19 cases
Changing trends in the clinical features of laryngeal tuberculosis: a report of 19 cases
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DOI：
10.1016/j.ijid.2009.05.002
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发表时间：
2010-03-01
影响因子：
8.4
通讯作者：
Wang, Shen-Qing
中科院分区：
文献类型：
--
作者：
Ling, Ling;Zhou, Shui-Hong;Wang, Shen-Qing
目的：探讨喉结核临床特征的变化趋势，以减少误诊和错误治疗。方法：回顾性分析1990年以前5例经病理证实的喉结与1998年以后14例喉结的临床特点。结果：1990年以前5例患者年龄19 ~ 41岁，平均32岁。最常见的主诉是吞咽伴系统症状和肺结核。喉后部常受累，病变多为溃疡性及多发。1998年以后14例患者年龄17 ~ 71岁，平均年龄49.9岁。最常见的主诉是声音嘶哑（71.4%）。最常见的病变部位为真声带（57.2%）。大多数肺状态正常的患者有单一的、非特异性的息肉样病变。频闪检查显示了四种不同的外观。结论：即使没有肺结核，喉结核也可能发生，其病变特征似乎更具非特异性。在喉部疾病的鉴别诊断中考虑结核是很重要的。(C) 2009年国际传染病学会。Elsevier Ltd.出版。版权所有。
Objective: This study was undertaken to evaluate the changing trends in the clinical features of laryngeal tuberculosis, with the goal of reducing misdiagnosis and incorrect treatment.Methods: A retrospective clinical analysis compared the clinical patterns in five cases with pathologically confirmed laryngeal tuberculosis seen before 1990 with those of 14 cases of laryngeal tuberculosis seen after 1998.Results: The five patients seen before 1990 ranged in age from 19 to 41 years of age, with a mean of 32 years. The most frequent chief complaint was odynophagia accompanying system symptoms and pulmonary tuberculosis. The posterior part of the larynx was commonly involved and the lesions tended to be ulcerative and multiple. The 14 patients seen after 1998 were aged from 17 to 71 years with a mean age of 49.9 years. The most frequent chief complaint was hoarseness (71.4%). The most common lesion site was in the true vocal cords (57.2%). Most of patients with normal lung status had single, nonspecific, polypoid lesions. Stroboscopy revealed four different appearances.Conclusions: Laryngeal tuberculosis may occur even without pulmonary tuberculosis, and the characteristics of the lesions appear to be more nonspecific. It is important to consider tuberculosis in the differential diagnosis of laryngeal disease. (C) 2009 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.