A novel feature of microsatellites in plants: a distribution gradient along the direction of transcription
A novel feature of microsatellites in plants: a distribution gradient along the direction of transcription
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DOI：
10.1016/s0014-5793(03)01041-x
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发表时间：
2003-11-06
期刊：
影响因子：
3.5
通讯作者：
Tomita, M
中科院分区：
文献类型：
--
作者：
Fujimori, S;Washio, T;Tomita, M
利用计算机分析了水稻和拟南芥转录区微卫星的特征。此外，同时分析了两种哺乳动物进行比较分析。我们的分析证实了一种新的植物特异性特征，其中微卫星密度沿着转录方向存在梯度。研究还证实，富含嘧啶的微卫星在转录起始位点附近被密集发现，特别是在两种植物中，而不是在哺乳动物中。我们的研究结果表明，位于高频率的微卫星在植物基因的5 '侧翼区可能作为调控基因表达的因素。(C)2003年欧洲生物化学学会联合会。Elsevier B.V.出版，保留所有权利。
A computer-based analysis was conducted to assess the characteristics of microsatellites in transcribed regions of rice and Arabidopsis. In addition, two mammals were simultaneously analyzed for a comparative analysis. Our analyses confirmed a novel plant-specific feature in which there is a gradient in microsatellite density along the direction of transcription. It was also confirmed that pyrimidine-rich microsatellites are found intensively near the transcription start sites, specifically in the two plants, but not in the mammals. Our results suggest that microsatellites located at high frequency in the 5'-flanking regions of plant genes can potentially act as factors in regulating gene expression. (C) 2003 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.