THE INFLUENCE OF REPEATED CAROTID PLAQUE HEMORRHAGES ON THE PRODUCTION OF CEREBROVASCULAR SYMPTOMS
THE INFLUENCE OF REPEATED CAROTID PLAQUE HEMORRHAGES ON THE PRODUCTION OF CEREBROVASCULAR SYMPTOMS
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DOI：
10.1067/mva.1986.avs0030857
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发表时间：
1986-06-01
影响因子：
4.3
通讯作者：
TRAVERS, H
中科院分区：
文献类型：
--
作者：
AMMAR, AD;ERNST, RL;TRAVERS, H
单一颈动脉斑块内出血与脑血管缺血症状的发生有关。我们无法重现这些结果，因此，我们的患者人群进行了重新调查，以确定重复斑块扩张的重要性及其与神经系统症状产生的可能关系。85例连续患者接受了95例颈动脉内膜切除术。斑块被分为三组：有偏侧症状，非偏侧症状和无症状的患者。显微镜下检查所有斑块是否有出血迹象，特别是反复出血。在偏侧症状组的44个斑块中有29个（66%）发现了重复破裂，在非偏侧症状组的19个斑块中有6个（32%），在无症状组的32个斑块中有12个（37%）。我们的结论是反复而不是单一斑块内出血是与特定脑血管缺血症状的产生相关的关键因素。
Single carotid intraplaque hemorrhage has been related to the occurrence of cerebrovascular ischemic symptoms. We were unable to reproduce these findings; therefore, our patient population was reinvestigated to ascertain the importance of repeated plaque hemorrhages and their possible relationship to the production of neurologic symptoms. Eighty-five consecutive patients underwent 95 carotid endarterectomies. Plaques were separated into three groups: those from patients with lateralizing symptoms, nonlateralizing symptoms, and no symptoms. All the plaques were inspected microscopically for evidence of hemorrhage, specifically, repeated hemorrhages. Repeated hemorrhages were found in 29 of 44 plaques (66%) in the lateralizing symptom group, 6 of 19 (32%) in the nonlateralizing symptom group, and 12 of 32 (37%) in the no symptom group. We conclude that repeated rather than single intraplaque hemorrhage is the critical factor related to the production of specific cerebrovascular ischemic symptoms.