Primary intraocular lymphoma: A review.
Primary intraocular lymphoma: A review.
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DOI：
10.1080/08820530500350498
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发表时间：
2006-07-01
影响因子：
1.7
通讯作者：
Foster, C Stephen
中科院分区：
文献类型：
--
作者：
Choi, John Y;Kafkala, Chrysanthi;Foster, C Stephen
原发性眼内淋巴瘤是一种原发性中枢神经系统淋巴瘤（PCNSL）。这是最常见的累及眼部的肿瘤假面舞症。其多变的眼部表现，加上在许多病例中，最初对疑似葡萄膜炎的皮质类固醇治疗的阳性反应，延迟了准确的诊断。高度怀疑是必要的，其次是组织活检与细胞学和辅助研究。目前的治疗是基于高剂量甲氨蝶呤和放射治疗的化疗。由于中枢神经系统受累，预后较差，但较新的治疗方法在延长生存方面取得了一些成功。
Primary intraocular lymphoma (PIOL) is a type of primary central nervous system lymphoma (PCNSL). It is the most common neoplastic masquerade syndrome involving the eye. Its protean ocular manifestations, plus in many cases the initial positive response to corticosteroid therapy for presumed uveitis, delay accurate diagnosis. A high index of suspicion is essential, followed by tissue biopsy with cytology and ancillary studies. Current treatment is based on chemotherapy featuring high-dose methotrexate and radiation therapy. Prognosis is poor due to CNS involvement, but newer therapies have had some success in prolonging survival.