Stress- and cue-induced cigarette craving: Effects of a family history of smoking
Stress- and cue-induced cigarette craving: Effects of a family history of smoking
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DOI：
10.1016/j.drugalcdep.2006.11.006
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发表时间：
2007-05-11
影响因子：
4.2
通讯作者：
Erblich, Joel
中科院分区：
文献类型：
--
作者：
Colamussi, Lauralea;Bovbjerg, Dana H.;Erblich, Joel
一级亲属中有多个吸烟者（FH+）的人更有可能是持续吸烟者。这种关系背后的机制尚不清楚。一项独立的研究表明，在暴露于吸烟暗示和压力源后，吸烟者对香烟的渴望程度更高，持续吸烟更常见。本研究通过实验验证了FH+吸烟者与FH-吸烟者相比会表现出更强的压力和线索诱导的渴望反应的假设。我们还探讨了这些影响中与性别和种族相关的差异。为此，160名吸烟者通过广告招募，并暴露于中性（换灯泡），压力（牙科工作）和吸烟（饭后点燃）的情况下，在受控的实验室条件下使用脚本引导的图像。参与者在每个条件之前和之后完成了渴望问卷。支持该假设，即使在控制吸烟史和习惯强度之后，FH+吸烟者（n = 86）比FH-吸烟者（n = 74）显示出对牙科和吸烟图像的更强的渴望反应（p < 0.05）。有趣的是，女性比男性有更高的压力-但不是吸烟线索诱导的渴望，FH+女性表现出最高水平的压力诱导的渴望。研究结果表明，通过一种机制，吸烟家族史导致戒烟成功率较差，特别是在女性中。(c)2006爱思唯尔爱尔兰有限公司保留所有权利。
Individuals with multiple smokers among first-degree relatives (FH+) are significantly more likely to be persistent smokers themselves. The mechanisms underlying this relationship are unknown. An independent line of research has suggested that persistent smoking is more common among smokers with heightened levels of cigarette craving after being exposed to smoking cues and stressors. The present study experimentally tested the hypothesis that FH+ smokers would exhibit stronger stress- and cue-induced craving reactions compared to FH- smokers. We also explored gender and ethnicity-related differences in these effects. To that end, 160 smokers were recruited by advertisement and exposed to neutral (changing a light bulb), stressful (dental work), and smoking (lighting up after a meal) situations, using script-guided imagery under controlled laboratory conditions. Participants completed craving questionnaires before and after each condition. Supporting the hypotheses, even after controlling smoking history and strength of habit, FH+ smokers (n = 86) displayed stronger craving reactions to both dental and smoking imagery (p's < 0.05) than FH- smokers (n = 74). Interestingly, women had higher stress-, but not smoking cue-induced cravings, than men, with FH+ women exhibiting the highest levels of stress-induced craving. Findings suggest a mechanism through which a family history of smoking leads to poorer cessation success, especially among women. (c) 2006 Elsevier Ireland Ltd. All rights reserved.