Anxiety, Depression and Sleep Disturbance in Female Constipation Predominant Irritable Bowel Syndrome
Anxiety, Depression and Sleep Disturbance in Female Constipation Predominant Irritable Bowel Syndrome
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女性便秘型肠易激综合症的焦虑、抑郁和睡眠障碍
DOI：
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发表时间：
2005
期刊：
影响因子：
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通讯作者：
H. Choi
中科院分区：
文献类型：
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作者：
S. Han;O. Lee;Y. Lee;Kwuybun Kim;B. Yoon;H. Choi
背景/目的：心理障碍和睡眠障碍常与肠易激综合征（IBS）相关。本报告的目的是评估便秘为主的女性肠易激综合征患者的焦虑、抑郁和睡眠障碍程度。方法：选取39例以便秘为主的女性IBS患者和53例健康对照者。采用Spielberger状态焦虑量表、Zung抑郁自评量表和韩国睡眠量表对焦虑、抑郁和睡眠障碍进行评估。评估焦虑、抑郁和睡眠障碍之间的相关性，并根据IBS症状的严重程度评估这些症状的程度。结果：便秘为主的女性IBS患者的焦虑平均得分高于对照组（p<0.001）。以便秘为主的女性IBS患者的抑郁平均评分高于对照组（p<0.001）。以便秘为主的女性肠易激综合征患者的睡眠障碍评分高于对照组（p<0.001）。患者焦虑情绪和抑郁情绪均高于对照组（r= 0.659, p<0.05）。患者焦虑、抑郁等心理困扰与睡眠主诉之间存在显著相关（r=- 0.368, r=- 0.567, p<0.05）。随着胃肠道症状严重程度的增加，患者焦虑（p=0.025）、抑郁情绪（p=0.009）和睡眠抱怨（p<0.001）增加。结论：便秘为主的女性IBS患者明显比健康对照组有更多的焦虑和抑郁特征，睡眠质量受损。（中华神经科杂志，2005;11:66-71）
Background/Aims: Psychological disturbances and sleep disturbances are frequently associated with the irritable bowel syndrome (IBS). The aim of this report was to evaluate the degree of anxiety, depression and sleep disturbance in female constipation-predominant IBS patients. Methods: In this study, 39 female constipation-predominant IBS patients and 53 healthy controls were included. Anxiety, depression and sleep disturbance were assessed with using Spielberger's state anxiety scale, Zung's self-rating depression scale and the Korean sleep scale. The correlations among anxiety, depression and sleep disturbance were evaluated, and the degrees of such symptoms according to the severity of the symptoms of IBS were evaluated. Results: The mean score of anxiety was higher in female constipation-predominant IBS patients than in the controls (p<0.001). The mean score of depression was higher in female constipation-predominant IBS patients than in the controls (p<0.001). The score for sleep disturbance was higher in the female constipation-predominant IBS patients than in the controls (p<0.001). The patients experienced more anxious moods and more depressive moods (r=.659, p<0.05). Also, significant correlations were found between such psychological distress as anxiety, depression and sleep complaints for the patients (r=-.368, r=-.567, p<0.05). The patients were more anxious (p=0.025), they had more depressed moods (p=0.009) and sleep complaints (p<0.001) as the severity of the gastrointestinal symptom increased. Conclusions: Female constipation-predominant IBS patients have significantly more anxious and depressive traits and an impaired quality of sleep than did the healthy controls. (Kor J Neurogastroenterol Motil 2005;11:66-71)