Increased phosphorylation rate of intermediate filaments during mitotic arrest.

Increased phosphorylation rate of intermediate filaments during mitotic arrest.
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有丝分裂停滞期间中间丝的磷酸化率增加。

DOI:
10.1016/0014-4827(81)90338-4
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发表时间:
1981
影响因子:
3.7
通讯作者:
Vogelstein,B
Vogelstein,B
中科院分区:
医学3区
文献类型:
--
作者:
Robinson,SI;Nelkin,B;Kaufmann,S;Vogelstein,B

文献摘要

被引文献

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A detergent insoluble 58 000 D polypeptide is phosphorylated at an increased rate during mitotic arrest in cultured Chinese hamster ovary cells. Using one-dimensional peptide mapping, this polypeptide was identified as a phosphorylated form of intermediate filament protein (IFP). The increased rate of phosphorylation is observed with either colcemid- or vinblastine-treated mitotic cells, but is not seen with similarly treated interphase cells.