Allogeneic mesenchymal stem cells transplantation in treatment of multiple sclerosis
Allogeneic mesenchymal stem cells transplantation in treatment of multiple sclerosis
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DOI：
10.1177/1352458509104590
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发表时间：
2009-05-01
影响因子：
5.8
通讯作者：
Sun, L.
中科院分区：
文献类型：
--
作者：
Liang, J.;Zhang, H.;Sun, L.
多发性硬化症（MS）是一种中枢神经系统的慢性自身免疫性疾病。脐带间充质干细胞具有免疫抑制作用。我们将间充质干细胞移植给难治性进展性MS患者，移植后病情稳定。我们假设间充质干细胞在体内具有有效的免疫抑制作用。多发性硬化症2009；15: 644 - 646。http://msj.sagepub.com
Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system. Umbilical cord derived mesenchymal stem cells are immunosuppressive. We transplanted mesenchymal stem cells in a patient with refractory progressive MS, and the disease course was stabilized after the transplantation. We postulate that mesenchymal stem cells have a potent immunosuppressive effect in vivo. Multiple Sclerosis 2009; 15: 644-646. http://msj.sagepub.com