Perimovement decrease of alpha/beta oscillations in the human nucleus accumbens
Perimovement decrease of alpha/beta oscillations in the human nucleus accumbens
复制标题
周围运动减少人类伏隔核的α/β振荡
DOI：
10.1152/jn.00142.2016
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发表时间：
2016
影响因子：
2.5
通讯作者：
Schoenfeld MA
中科院分区：
文献类型：
--
作者：
Stenner MP;Dürschmid S;Rutledge RB;Zaehle T;Schmitt FC;Kaufmann J;Voges J;Heinze HJ;Dolan RJ;Schoenfeld MA
人类伏隔核被认为通过对当前动作结果的评估，在指导未来的动作选择方面发挥着重要作用。在这里，我们为动作准备过程中更直接的，即在线的作用提供了电生理学证据。我们记录了接受脑深部刺激手术的癫痫患者伏隔核的局部场电位。我们发现，在运动之前和前后，α/β振荡(10-30赫兹)的功率持续下降。在8名患者中有7名患者观察到了这种周围性α/β去同步化，在连续反应时间任务中指示运动之前以及在决策任务中自定步调、刻意选择之前都存在。感觉运动皮质和丘脑底核中类似的β下降与运动准备和执行直接相关。我们的结果支持人类伏隔核在动作准备和执行中起直接作用的观点。
The human nucleus accumbens is thought to play an important role in guiding future action selection via an evaluation of current action outcomes. Here we provide electrophysiological evidence for a more direct, i.e., online, role during action preparation. We recorded local field potentials from the nucleus accumbens in patients with epilepsy undergoing surgery for deep brain stimulation. We found a consistent decrease in the power of alpha/beta oscillations (10–30 Hz) before and around the time of movements. This perimovement alpha/beta desynchronization was observed in seven of eight patients and was present both before instructed movements in a serial reaction time task as well as before self-paced, deliberate choices in a decision making task. A similar beta decrease over sensorimotor cortex and in the subthalamic nucleus has been directly related to movement preparation and execution. Our results support the idea of a direct role of the human nucleus accumbens in action preparation and execution.