Understanding the formation of CuS concave superstructures with peroxidase-like activity
Understanding the formation of CuS concave superstructures with peroxidase-like activity
复制标题
了解具有过氧化物酶样活性的 CuS 凹形超结构的形成
DOI：
10.1039/c2nr30310h
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发表时间：
2012-01-01
期刊：
影响因子：
6.7
通讯作者：
Zheng, Zhi
中科院分区：
文献类型：
--
作者：
He, Weiwei;Jia, Huimin;Zheng, Zhi
在无表面活性剂和模板剂的条件下，通过简单的溶剂热反应，在乙醇溶液中成功地制备了硫化铜（CuS）凹多面体超结构（CPS）。制备了两个典型的、轮廓分明的、高对称性的CuS凹多面体，形成凹截顶的立方八面体和二十面体。考察了反应时间、反应温度、不同铜离子和硫源对CuS CPSs生成的影响，并结合气相色谱-质谱联用技术对CuS CPSs的生成机理进行了探讨。更重要的是，我们首次发现，CuS CPS表现出内在的过氧化物酶样活性，因为它们可以在过氧化氢的存在下快速催化典型的辣根过氧化物酶（HRP）底物3，3 '，5，5'-四甲基联苯胺（TMB）和邻苯二胺（OPD）的氧化。除了最近关于Fe 3 O 4纳米颗粒和碳纳米结构上的过氧化物酶模拟物的发现之外，我们的研究结果还表明了一种新的过氧化物酶模拟物的候选者。这可能为CuS微纳结构在生物检测、生物催化和环境监测等方面开辟新的应用领域。
Copper sulfide (CuS) concave polyhedral superstructures (CPSs) have been successfully prepared in an ethanolic solution by a simple solvothermal reaction without the use of surfactants or templates. Two typical well defined, high symmetry CuS concave polyhedrons, forming a concave truncated cuboctahedron and icosahedron were prepared. The effect of the reaction time, temperature and different Cu ion and sulfur sources on the formation of CuS CPSs were investigated and a possible formation mechanism was proposed and discussed based on gas chromatography-mass spectrometry. More importantly, we found, for the first time, that the CuS CPSs exhibit intrinsic peroxidase-like activity, as they can quickly catalyze the oxidation of typical horseradish peroxidase (HRP) substrates, 3,3', 5,5'-tetramethylbenzidine (TMB) and o-phenylenediamine (OPD), in the presence of hydrogen peroxide. In addition to the recent discoveries regarding peroxidase mimetics on Fe3O4 NPs and carbon nanostructures, our findings suggest a new kind of candidate for peroxidase mimics. This may open up a new application field of CuS micro-nano structures in biodetection, biocatalysis and environmental monitoring.