Relative weight and race influence average age at menarche: Results from two nationally representative surveys of US girls studied 25 years apart
Relative weight and race influence average age at menarche: Results from two nationally representative surveys of US girls studied 25 years apart
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DOI：
10.1542/peds.111.4.844
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发表时间：
2003-04-01
期刊：
影响因子：
8
通讯作者：
Must, A
中科院分区：
文献类型：
--
作者：
Anderson, SE;Dallal, GE;Must, A
目标。1)用具有全国代表性的美国数据来确定初潮是否发生在20世纪90年代比25年前更早。2)评估月经初潮的发生与体重状况和种族的关系在这段时间内是否发生了变化。对第二次和第三次全国健康体检调查(1963-1970年)中女孩的相对体重、种族和月经状况与第三次全国健康与营养调查(1988-1994年)的结果进行了比较。用概率分析来确定两个调查期的月经初潮平均年龄。Logistic回归用于评估相对体重与达到月经初潮的可能性之间的关系。月经初潮的平均年龄从12.75岁下降到12.54岁，在两次调查之间的25年里，10岁到15岁的女孩超过体重指数第85个百分位数的比例从16%上升到27%。在控制了年龄和种族后，较高的相对体重与达到月经初潮的可能性增加密切相关。黑人女孩月经初潮的平均年龄低于白人女孩，这与相对体重的影响无关。这些来自两个具有全国代表性的美国女孩样本的分析表明，在1963-1970年和1988-1994年间，月经初潮的平均年龄下降了大约2.5个月。与此同时，体重指数z-Score的人口分布也同时向更高的相对体重转移。
Objectives. 1) To establish with nationally representative US data whether menarche occurred earlier in the 1990s than it had 25 years before. 2) To assess whether the occurrence of menarche in relation to weight status and race had changed over this time period.Methods. Relative weight, race, and menarcheal status of girls in the National Health Examination Survey cycles II and III (1963-1970) were compared with results from the Third National Health and Nutrition Examination Survey (1988-1994). Probit analysis was used to determine the average age at menarche during the 2 survey periods. Logistic regression was used to assess the association of relative weight to likelihood of having reached menarche.Results. The average age at menarche dropped from 12.75 to 12.54 years, and the percentage of girls between 10 and 15 years old who were above the 85th percentile for body mass index increased from 16% to 27% over the 25 years between the 2 surveys. Higher relative weight was strongly associated with increased likelihood of having reached menarche after controlling for age and race. Black girls had a lower average age at menarche than did white girls, which was independent of the effect of relative weight.Conclusions. These analyses from 2 nationally representative samples of US girls suggest a drop of about 2 1/2 months in the average age of menarche during the time period between 1963-1970 and 1988-1994. This was paralleled by a concurrent shift in the population distribution of body mass index z-score toward higher relative weights.