Design and engineering of multifunctional silica-supported cooperative catalysts
Design and engineering of multifunctional silica-supported cooperative catalysts
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DOI：
10.1016/j.cattod.2018.11.040
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发表时间：
2019-08-15
期刊：
影响因子：
5.3
通讯作者：
Jonas, Alain M.
中科院分区：
文献类型：
--
作者：
Fernandes, Antony E.;Jonas, Alain M.
在介孔二氧化硅上固定多个功能基团为模拟酶的独特设计原理和性能提供了机会。在这个方向上，必须掌握活性表面结合分子的协同行为，以获得与溶液中的母体系统相比具有增强或新颖性能的多相、可回收催化剂。随着溶胶-凝胶和表面化学的发展，制备能够结合联合收割机大部分有机化学活化方式的二氧化硅负载多功能催化剂成为可能。进一步调整受限活化官能团的表面比率和接近度提供了改进活性位点内协同相互作用的可能性的方法。然而，表面官能团的空间分布的系统评估和工程，这往往是随机排列在孔道内，提出了下一个关键的挑战，以更合理的设计生物启发的负载型催化剂。
The immobilization of multiple functional groups on mesoporous silica has provided opportunities to emulate the unique design principles and performances of enzymes. In this direction, it is essential to master the cooperative behavior of active surface-bound molecules to arrive at heterogeneous, recyclable catalysts with enhanced or novel properties compared to the parent system in solution. With the advances in sol-gel and surface chemistry, it is now possible to prepare silica-supported multifunctional catalysts that can combine most of the activation modes of organic chemistry. Further tailoring the surface ratio and proximity of the confined activating functional groups affords ways to refine the probability of synergistic interactions within the active site. Yet, the systematic evaluation and engineering of the spatial distribution of surface functional groups, which are more often randomly arranged within the pore channels, rises the next key challenge towards a more rational design of bioinspired supported catalysts.