Total Delay in Treatment among Smear Positive Pulmonary Tuberculosis Patients in Five Primary Health Centers, Southern Ethiopia: A Cross Sectional Study
Total Delay in Treatment among Smear Positive Pulmonary Tuberculosis Patients in Five Primary Health Centers, Southern Ethiopia: A Cross Sectional Study
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DOI：
10.1371/journal.pone.0102884
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发表时间：
2014-07-21
期刊：
影响因子：
3.7
通讯作者：
Teshome, Wondu
中科院分区：
文献类型：
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作者：
Asefa, Anteneh;Teshome, Wondu
简介：结核病（TB）的全球负担仍然巨大。结核病诊断的延误可能导致社区中的传染病库增加，并使疾病在就诊时处于更晚期的状态，从而增加死亡风险。本研究旨在确定涂阳肺结核（PTB）patients.Methods治疗前的总延迟：2012年6月至12月，在埃塞俄比亚南部的5个初级卫生中心进行了一项基于卫生机构的横断面研究。共328例涂阳肺结核患者入组研究。一个结构化的和预先测试的问卷调查。计算患者、诊断和治疗延迟的中位数，以确定总延迟。结果：患者、诊断、治疗和总延误的中位天数分别为30（IQR：20.2，60）、7（IQR：3，14）、3（IQR：1，4）和45（IQR：34.5，69.5）d。49%的患者在出现症状后45天内未开始治疗（总延迟）（男性59.5%，女性39.2%; P
Introduction: The global burden of Tuberculosis (TB) remains enormous. Delay in TB diagnosis may lead to a higher infectious pool in the community and a more advanced disease state at presentation increasing the risk of mortality. This study is conducted to determine the total delay before treatment among smear positive Pulmonary Tuberculosis (PTB) patients.Methods: A health institution based cross sectional study was conducted in five primary health centers in southern Ethiopia from June to December 2012. A total of 328 smear positive PTB patients were enrolled in the study. A structured and pretested questionnaire was used. Median patient, diagnostic, and treatment delays were calculated to determine the total delay. Multiple logistic regression analysis was used to identify factors associated with total delay.Results: The median patient, diagnostic, treatment and total delays measured in days were 30 (IQR 20.2, 60), 7 (IQR: 3, 14), 3 (IQR: 1, 4) and 45 (IQR: 34.5, 69.5) days respectively. Patients for whom treatment was not initiated within 45 days of onset of symptom(s) (total delay) constituted 49% of the study participants (59.5% among males and 39.2% among females; P