A comparison between acyclovir and trifluorothymidine ophthalmic ointment in the treatment of epithelial dendritic keratitis
A comparison between acyclovir and trifluorothymidine ophthalmic ointment in the treatment of epithelial dendritic keratitis
复制标题
阿昔洛韦与三氟胸苷眼膏治疗上皮性树枝状角膜炎的比较
作者：
G. Høvding
本文报告了50例上皮性单纯疱疹性角膜炎患者的随机双盲研究结果。25例患者接受3%阿昔洛韦眼用软膏，其他25例患者接受2%三氟胸苷（TFT）眼用软膏。在上皮溃疡愈合前，2个研究组的平均治疗持续时间分别为6.7天和5.9天（无统计学显著差异）。无环鸟苷组2例（8%）和TFT组1例（4%）在治疗14天内未能治愈。未记录临床显著不良反应。
Abstract This report presents the results of a double blind randomized study comprising 50 patients with epithelial herpes simplex keratitis. Twenty‐five patients received 3% acyclovir ophthalmic ointment, the other 25 patients 2% trifluorothymidine (TFT) ophthalmic ointment. The mean duration of treatment in the 2 study groups before healing of the epithelial ulceration was obtained was 6.7 days and 5.9 days, respectively (no statistically significant difference). Two patients (8%) in the acyclovir group and 1 patient (4%) in the TFT group failed to heal within 14 days of treatment. No clinically significant adverse effects were recorded.