Sagittal laser optical tomography for imaging of rheumatoid finger joints
Sagittal laser optical tomography for imaging of rheumatoid finger joints
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DOI：
10.1088/0031-9155/49/7/005
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发表时间：
2004-04-07
影响因子：
3.5
通讯作者：
Beuthan, J
中科院分区：
文献类型：
--
作者：
Hielscher, AH;Klose, AD;Beuthan, J
我们提出了一种新的光学断层成像系统，旨在确定通过手指关节的矢状面中的光学特性的二维空间分布。该系统将单个激光二极管和单个硅光电探测器集成到扫描设备中，该扫描设备记录通过手指传输的空间分辨光强度。这些数据被输入到基于模型的迭代图像重建（MOBIIR）方案，该方案使用辐射传输（ERT）方程作为光通过组织传播的前向模型。我们已经使用该系统获得断层图像的六个近端指间手指关节从两个类风湿性关节炎患者。将光学图像与临床症状和超声图像进行比较。
We present a novel optical tomographic imaging system that was designed to determine two-dimensional spatial distribution of optical properties in a sagittal plane through finger joints. The system incorporates a single laser diode and a single silicon photodetector into a scanning device that records spatially resolved light intensities as they are transmitted through a finger. These data are input to a model-based iterative image reconstruction (MOBIIR) scheme, which uses the equation of radiative transfer (ERT) as a forward model for light propagation through tissue. We have used this system to obtain tomographic images of six proximal interphalangeal finger joints from two patients with rheumatoid arthritis. The optical images were compared to clinical symptoms and ultrasound images.