Severity of Depression and Magnitude of Productivity Loss

Severity of Depression and Magnitude of Productivity Loss
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DOI:
10.1370/afm.1260
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发表时间:
2011-07-01
影响因子:
4.4
通讯作者:
Whitebird, Robin
Whitebird, Robin
中科院分区:
医学1区
文献类型:
--
作者:
Beck, Arne;Crain, A. Lauren;Whitebird, Robin

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目的抑郁症与工作功能降低有关,包括缺勤、生产力受损和工作保持率下降。然而,很少有研究考察抑郁症症状在一系列严重程度上与大量异质患者群体中工作损害的程度的关系。我们评估了开始抑郁症治疗的患者中抑郁症症状严重程度和生产力损失之间的关系。方法数据来自参与DIAMOND(明尼苏达州抑郁症改善:提供新方向)倡议的患者,该倡议是一个全州范围的质量改进合作,以提供增强的抑郁症护理。对新开始服用抗抑郁药物的患者进行了患者健康问卷9项筛选(PHQ-9)(衡量抑郁症状严重程度)、工作生产力和活动受损(WPAI)问卷(衡量生产力下降)以及健康状况和人口统计学项目的调查。对人口统计学和健康状况进行调整的一般线性模型显示,抑郁症状严重程度和生产力损失之间存在显著的线性单调关系:PHQ-9得分每增加1分,患者的平均生产力损失就会增加1.65%(P<.001)。即使是轻微的抑郁症状也与工作功能的下降有关。全职与兼职的就业状况、自我报告的一般或较差的健康状况与良好、非常好或良好的健康状况也与生产力的丧失有关(分别为P<.001和P=.045)。结论本研究显示了抑郁症状的严重程度与工作功能之间的关系,并表明即使是轻微的抑郁程度也与生产力的丧失有关。雇主可能会发现,在整个抑郁症严重程度的连续体中,投资于对抑郁员工进行有效治疗是有益的。
PURPOSE Depression is associated with lowered work functioning, including absences, impaired productivity, and decreased job retention. Few studies have examined depression symptoms across a continuum of severity in relationship to the magnitude of work impairment in a large and heterogeneous patient population, however. We assessed the relationship between depression symptom severity and productivity loss among patients initiating treatment for depression.METHODS Data were obtained from patients participating in the DIAMOND (Depression Improvement Across Minnesota: Offering a New Direction) initiative, a statewide quality improvement collaborative to provide enhanced depression care. Patients newly started on antidepressants were surveyed with the Patient Health Questionnaire 9-item screen (PHQ-9), a measure of depression symptom severity; the Work Productivity and Activity Impairment (WPAI) questionnaire, a measure of loss in productivity; and items on health status and demographics.RESULTS We analyzed data from the 771 patients who reported being currently employed. General linear models adjusting for demographics and health status showed a significant linear, monotonic relationship between depression symptom severity and productivity loss: with every 1-point increase in PHQ-9 score, patients experienced an additional mean productivity loss of 1.65% (P < .001). Even minor levels of depression symptoms were associated with decrements in work function. Full-time vs part-time employment status and self-reported fair or poor health vs excellent, very good, or good health were also associated with a loss of productivity (P < .001 and P = .045, respectively).CONCLUSIONS This study shows a relationship between the severity of depression symptoms and work function, and suggests that even minor levels of depression are associated with a loss of productivity. Employers may find it beneficial to invest in effective treatments for depressed employees across the continuum of depression severity.