CONCURRENT ISOLATION FROM PATIENT OF 2 ARBOVIRUSES - CHIKUNGUNYA AND DENGUE TYPE 2
CONCURRENT ISOLATION FROM PATIENT OF 2 ARBOVIRUSES - CHIKUNGUNYA AND DENGUE TYPE 2
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DOI：
10.1126/science.157.3794.1307
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发表时间：
1967-01-01
期刊：
影响因子：
56.9
通讯作者：
CAREY, DE
中科院分区：
文献类型：
--
作者：
MYERS, RM;CAREY, DE
基孔肯雅病毒和登革热2型病毒是从1964年10月在印度南部韦洛雷的基督教医学院医院就诊的登革热样疾病急性期患者的单一血液标本中分离出来的。在从该患者采集的系列血液标本中，这两种病毒的抗体增加。描述了在存在具有短孵育期的试剂的情况下在小鼠中暴露具有长孵育期的试剂（例如登革热）的技术。
Chikungunya virus and dengue type 2 virus were isolated from a single blood specimen taken from a patient in the acute phase of a dengue-like illness seen at Christian Medical College Hospital, Vellore, South India, in October 1964. In serial blood specimens collected from this patient there was an increase in antibody to these same 2 viruses. The technique for unmasking an agent (such as dengue) with a long incubation period in mice in the presence of an agent with a short incubation period is described.