Organization of neuronal microtubules in the nematode Caenorhabditis elegans.
Organization of neuronal microtubules in the nematode Caenorhabditis elegans.
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DOI：
10.1083/jcb.82.1.278
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发表时间：
1979-07
期刊：
影响因子：
--
通讯作者：
Thomson JN
中科院分区：
文献类型：
--
作者：
Chalfie M;Thomson JN
我们研究了线虫线虫神经元中微管的组织。六个神经元，我们称之为微管细胞，含有成束的深色微管，在连续切片的电子显微镜下很容易追踪到这些微管。对这些细胞中单个微管的重建表明，与细胞突起的长度相比，大多数(如果不是全部)微管都很短。平均微管长度因细胞类型而异。微管的排列给每一束提供了一个整体的极性：微管的远端在束的外部，而近端优先在束的内部。远端和近端各有一个特征的外观，表明这些微管可能有它们自己的极性。线虫其他神经元突起中的短微管也被观察到。
We have studied the organization of microtubules in neurons of the nematode Caenorhabditis elegans. Six neurons, which we call the microtubule cells, contain bundles of darkly staining microtubules which can be followed easily in serial-section electron micrographs. Reconstruction of individual microtubules in these cells indicate that most, if not all, microtubules are short compared with the length of the cell process. Average microtubule length varies characteristically with cell type. The arrangement of microtubules gives an overall polarity to each bundle: the distal ends of the microtubles are on the outside of the bundle, whereas the proximal ends are preferentially inside. The distal and proximal ends each have a characteristic appearance indicating that these microtubules may have a polarity of their own. Short microtubules in processes of other neurons in C. elegans have also been observed.