The influence of training characteristics on the effect of aerobic exercise training in patients with chronic heart failure: A meta-regression analysis

The influence of training characteristics on the effect of aerobic exercise training in patients with chronic heart failure: A meta-regression analysis
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训练特征对慢性心力衰竭患者有氧运动训练效果影响的Meta回归分析

DOI:
10.1016/j.ijcard.2016.01.207
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发表时间:
2016-04-01
影响因子:
3.5
通讯作者:
Kemps, H. M.
Kemps, H. M.
中科院分区:
医学2区
文献类型:
--
作者:
Vromen, T.;Kraal, J. J.;Kemps, H. M.

文献摘要

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尽管有氧运动训练已被证明是治疗慢性心力衰竭患者的一种有效方法,但关于训练计划的设计以及哪些训练特征是提高运动能力的最强决定因素,一直存在争议。因此,我们进行了元回归分析,以确定训练特征对慢性心力衰竭患者有氧运动训练计划运动能力提高的个体效果的排名。我们重点研究了四个训练特征:训练频率、训练持续时间、训练强度和训练时长,以及它们的乘积;总能量消耗。对随机对照试验进行了系统的文献搜索,比较了持续有氧运动训练和日常护理。我们的分析包括17篇独特的文章。总能量消耗是唯一对运动能力提高有显著影响的训练特征。然而,结果主要由一项试验(HF-ACTION试验)主导,占患者总数的90%,与其他研究相比,结果显示出有争议的结果。不包括HF-ACTION试验的重复分析证实,运动能力的增加主要由总能量消耗决定,其次是训练频率、训练时间和训练强度。这些结果表明,训练计划的设计需要以高总能量消耗为主要目标。增加训练频率和课时似乎能最大程度地提高运动能力。(C)2016爱思唯尔爱尔兰有限公司。保留所有权利。
Although aerobic exercise training has shown to be an effective treatment for chronic heart failure patients, there has been a debate about the design of training programs and which training characteristics are the strongest determinants of improvement in exercise capacity. Therefore, we performed a meta-regression analysis to determine a ranking of the individual effect of the training characteristics on the improvement in exercise capacity of an aerobic exercise training program in chronic heart failure patients. We focused on four training characteristics; session frequency, session duration, training intensity and program length, and their product; total energy expenditure. A systematic literature search was performed for randomized controlled trials comparing continuous aerobic exercise training with usual care. Seventeen unique articles were included in our analysis. Total energy expenditure appeared the only training characteristic with a significant effect on improvement in exercise capacity. However, the results were strongly dominated by one trial (HF-action trial), accounting for 90% of the total patient population and showing controversial results compared to other studies. A repeated analysis excluding the HF-action trial confirmed that the increase in exercise capacity is primarily determined by total energy expenditure, followed by session frequency, session duration and session intensity. These results suggest that the design of a training program requires high total energy expenditure as a main goal. Increases in training frequency and session duration appear to yield the largest improvement in exercise capacity. (C) 2016 Elsevier Ireland Ltd. All rights reserved.