ADVERSE HEALTH-EFFECTS OF LEAD AT LOW EXPOSURE LEVELS - TRENDS IN THE MANAGEMENT OF CHILDHOOD LEAD-POISONING
ADVERSE HEALTH-EFFECTS OF LEAD AT LOW EXPOSURE LEVELS - TRENDS IN THE MANAGEMENT OF CHILDHOOD LEAD-POISONING
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DOI：
10.1016/0300-483x(94)02963-u
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发表时间：
1995-03-31
期刊：
影响因子：
4.5
通讯作者：
ROSEN, JF
中科院分区：
文献类型：
--
作者：
ROSEN, JF
一个广泛的数据库提供了一个直接的联系之间的低水平的铅暴露在早期发展和赤字的神经行为认知表现明显的儿童后期到青春期。这些一致的研究表明，在血铅水平至少低至10微克/分升时，铅会产生一系列神经毒性和其他不良影响。联邦机构和咨询小组将儿童铅中毒重新定义为BPb，水平为10 μ g/dl。在更详细地讨论这些研究之前，必须认识到这种完全可以预防的疾病在数百万美国儿童中的普遍性。
An extensive database has provided a direct link between low-level lead exposure during early development and deficits in neurobehavioral-cognitive performance evident late in childhood through adolescence. These consistent studies have demonstrated the presence of a constellation of neurotoxic and other adverse effects of lead at blood lead (BPb) levels at least as low as 10 mu g/dl). Federal agencies and advisory groups have redefined childhood lead poisoning as a BPb, level of 10 mu g/dl. Before discussing some of these studies in greater detail, the pervasiveness of this entirely preventable disease today in millions of American children must be recognized.