Personalized treatment of gynecological cancer according to age and symptom benefit
Personalized treatment of gynecological cancer according to age and symptom benefit
复制标题
根据年龄和症状获益的妇科癌症个体化治疗
DOI：
10.1007/978-981-19-4711-7_9
复制
发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Inoue D
中科院分区：
文献类型：
--
作者：
Yoshida Y;Inoue D
由于缺乏老年人妇科癌症治疗的既定指南，目前的治疗计划和政策是根据医生的经验，参考非老年和健康老年患者的数据，与患者和家属协商制定的。近年来，一种针对老年妇科肿瘤的个体化治疗的新理念开始确立。在老年癌症的治疗中，能够接受适用于健康的非老年患者的标准治疗的患者被认为是“适合”，而不能接受这种治疗的患者被认为是“不适合”。适宜性的判断不仅需要对个体差异和日历年龄进行综合评价，还需要对老年患者的身心残疾、社会和经济问题以及医疗决策进行综合评价。特别是，当认知功能下降时，确认患者的意图可能会成为确定治疗计划的障碍。在这种情况下，采用对老年人的综合评价来实现功能评估。本综述的目的是阐明老年妇科癌症患者手术和化疗的现状，并讨论未来的问题。
Since established guidelines for the treatment of gynecological cancers in the elderly are lacking, decisions regarding the treatment plan and policy are currently made in consultation with the patient and family based on the doctor’s experience, referring to data from non-elderly and healthy elderly patients. Recently, a new concept of individualized treatment for gynecological cancer in the elderly has started to be established. In the treatment of cancer in the elderly, patients who can receive the standard treatment applicable to healthy non-elderly patients are considered “fit,” while those who cannot receive such treatment are considered “unfit.” Judgment of suitability requires a comprehensive evaluation of not only individual differences and calendar age, but also physical and mental disabilities, social and economic problems, and medical policy decisions in the case of elderly patients. In particular, when cognitive functions are declining, confirmation of the patient’s intentions can represent an obstacle to determining a treatment plan. In such cases, a comprehensive evaluation of the elderly is used to achieve functional assessment. The purpose of this review was to clarify the current status of surgery and chemotherapy for elderly gynecological cancer patients and to discuss future issues.