ISOLATION AND CHARACTERIZATION OF A CYTOTOXIC METABOLITE OF TALAROMYCES-BACILLOSPORUS
ISOLATION AND CHARACTERIZATION OF A CYTOTOXIC METABOLITE OF TALAROMYCES-BACILLOSPORUS
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DOI：
10.1128/aem.61.3.941-943.1995
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发表时间：
1995-03-01
影响因子：
4.4
通讯作者：
UENO, Y
中科院分区：
文献类型：
--
作者：
ISHII, K;ITOH, T;UENO, Y
从水稻上培养的杆状芽孢杆菌IFO 8397菌株中分离到一种细胞毒性代谢产物--塔拉罗毒素。对该毒素的结构进行了分析，发现该毒素含有一个通过共轭三烯与反式-Delta(1)-八达林相连的吡咯里西二酮。
A cytotoxic metabolite, talarotoxin, was isolated from a fungus, Talaromyces bacillosporus IFO 8397, cultured on rice. The structure of the toxin was elucidated and found to contain a pyrrolizidinedione connected with a trans-Delta(1)-octalin through a conjugated triene.