Compressed-Sensing Accelerated 3-Dimensional Magnetic Resonance Cholangiopancreatography Application in Suspected Pancreatic Diseases
Compressed-Sensing Accelerated 3-Dimensional Magnetic Resonance Cholangiopancreatography Application in Suspected Pancreatic Diseases
复制标题
压缩感知加速三维磁共振胰胆管造影：在疑似胰腺疾病中的应用。
DOI：
10.1097/rli.0000000000000421
复制
发表时间：
2018-03-01
影响因子：
6.7
通讯作者：
Xue, Huadan
中科院分区：
文献类型：
--
作者：
Zhu, Liang;Wu, Xi;Xue, Huadan
目的：本研究的目的是前瞻性地评估压缩感知（CS）加速三维（3D）磁共振胰胆管造影（MRCP）原型方案的图像质量、胰管可见性和胰管相关病变的诊断性能，并将其与常规3D MRCP方案在疑似胰腺疾病患者中的诊断性能进行比较。材料和方法：机构审查委员会批准了这项前瞻性研究，所有患者都提供了书面知情同意书。共80例患者（47例男性和33例女性;中位年龄57岁;年龄范围24-87岁）在3.0 T下接受了3D MRCP。在每例患者中以随机顺序执行三种方案：CS屏气（BH）方案、CS导航器触发（NT）方案和常规NT方案。记录每个方案的采集时间。图像质量和导管可见性由2名放射科医师在5点量表上随机独立评定，他们对协议不知情。生成受试者工作特征曲线，并使用曲线下面积（A（z）值）比较每种方案在导管相关病变中的诊断性能。CS-BH的采集时间为17秒，CS-NT方案的采集时间为134.1 +/-33.5秒，两者均显著短于常规NT方案（364.7 +/-78.4秒;均P < 0.01）。CS-BH MRCP伪影明显少于CS-NT和常规NT（均P < 0.01）。3种方法对胆管的显示均相似，但CS-NT和常规NT MRCP对胰管的显示优于CS-BH MRCP（近、中、远段均P < 0.05）。结论：压缩传感-NT MRCP对胰管异常、长段胰管狭窄、异常分支管、囊性病变与胰管交通的检出率最高（平均A（z）值为0.943-0.983）。压缩感知-NT MRCP显示了对导管相关病变的上级诊断准确性。
Objectives: The aims of this study were to prospectively evaluate image quality, duct visibility, and diagnostic performance in duct-related pathologies of compressed-sensing (CS) accelerated 3-dimensional (3D) magnetic resonance cholangiopancreatography (MRCP) prototype protocols and compare these with those of conventional 3D MRCP protocol in patients with suspected pancreatic diseases.Material and Methods: The institutional review board approved this prospective study and all patients provided written informed consent. A total of 80 patients (47 men and 33 women; median age, 57 years; age range, 24-87 years) underwent 3D MRCP at 3.0 T. Three protocols were performed in each patient in random order: CS breath-hold (BH) protocol, CS navigator-triggered (NT) protocol, and conventional NT protocol. The acquisition time of each protocol was recorded. Image quality and duct visibility were independently rated in random order on a 5-point scale by 2 radiologists, who were blinded to the protocols. Receiver operating characteristic curves were generated, and area under the curve (A(z) value) was used to compare the diagnostic performance of each protocol in duct-related pathologies.Results: Acquisition time was 17 seconds for the CS-BH and 134.1 +/- 33.5 seconds for the CS-NT protocol, both being significantly shorter than the conventional NT protocol (364.7 +/- 78.4 seconds; both P < 0.01). The CS-BH MRCP protocol showed significantly less artifacts compared with the CS-NT and conventional NT protocols (both P < 0.01). Visualization of bile ducts was comparable in all 3 protocols, whereas CS-NT and conventional NT MRCP depicted pancreatic duct better than CS-BH MRCP did (for proximal, middle, and distal segment; all P < 0.05). Compressed-sensing-NT MRCP had the highest diagnostic performance for detecting ductal anomalies, long-segment duct stenosis, abnormal branch ducts, and communication between cystic lesion and pancreatic duct (mean A(z) value, 0.943-0.983).Conclusions: Compressed-sensing MRCP is feasible in patients with suspected pancreatic diseases. Compressed-sensing-NT MRCP demonstrated superior diagnostic accuracy for duct-related pathologies.