Biocompatible phosphatidylcholine bilayer coated on magnetic nanoparticles and their application in the extraction of several polycyclic aromatic hydrocarbons from environmental water and milk samples.
Biocompatible phosphatidylcholine bilayer coated on magnetic nanoparticles and their application in the extraction of several polycyclic aromatic hydrocarbons from environmental water and milk samples.
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DOI：
10.1016/j.chroma.2012.03.056
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发表时间：
2012-05
期刊：
影响因子：
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通讯作者：
Shengxiao Zhang;Hongyun Niu;Yuanyuan Zhang;Junshen Liu;Yali Shi;Xiaole Zhang;Yaqi Cai
中科院分区：
文献类型：
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作者：
Shengxiao Zhang;Hongyun Niu;Yuanyuan Zhang;Junshen Liu;Yali Shi;Xiaole Zhang;Yaqi Cai
将磷脂酰胆碱（PC）包覆在磁性纳米颗粒上形成脂质双层，作为固相萃取（SPE）吸附剂，用于富集环境水样和牛奶样品中的多环芳烃（PAHs）。采用改进的干脂膜水合法将脂质双层包覆在Fe 3 O 4纳米颗粒上。所得Fe 3 O 4/PC可以很容易地从溶液中分离，并表现出良好的吸附性能的有机污染物。用0.1g吸附剂即可从500 mL水溶液中萃取多环芳烃，用6 mL乙腈解吸。该方法提取时间为10 min，磁分离时间为5 min，快速。该方法已成功应用于环境水样和牛奶样品中多环芳烃的测定。检测限在0.2-0.6ngL-1之间。水样加标回收率为89%~ 115%，相对标准偏差为1%~ 8%。对于加标牛奶样品，RSD是令人满意的（1-9%），但回收率相对较低（42-62%）。我们展示了Fe 3 O 4/PC吸附剂在环境水和生物样品分析中的潜力。
In this work, phosphatidylcholine (PC) was coated on magnetic nanoparticles to form lipid bilayer as solid-phase extraction (SPE) sorbents for the enrichment of polycyclic aromatic hydrocarbons (PAHs) from environmental water and milk samples. The lipid bilayer was coated on Fe3O4nanoparticles using a modified dry lipid film hydration method. The resulted Fe3O4/PC could be readily isolated from solution with a magnet, and exhibited excellent adsorption performance to organic pollutants. Only 0.1g of sorbents was enough to extract PAHs from 500mL aqueous solution, and 6mL of acetonitrile was required to desorb them. The method was fast and relied on 10min extraction time and 5min magnetic separation. The proposed method was successfully applied to determine PAHs in some environmental water and milk samples. The detection limit was in the range of 0.2–0.6ngL−1. The recoveries of the spiked water samples ranged from 89% to 115% with relative standard deviations (RSD) varying from 1% to 8%. For spiked milk samples, RSD was satisfactory (1–9%), but the recoveries were relatively low (42–62%). We show the potentials of Fe3O4/PC sorbents in environmental water and biological sample analyses.