Effects of a restricted sleep regimen on ambulatory blood pressure monitoring in normotensive subjects

Effects of a restricted sleep regimen on ambulatory blood pressure monitoring in normotensive subjects
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DOI:
10.1016/0895-7061(95)00389-4
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发表时间:
1996-05-01
影响因子:
3.2
通讯作者:
Fogari, R
Fogari, R
中科院分区:
医学3区
文献类型:
--
作者:
Lusardi, P;Mugellini, A;Fogari, R

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本文研究了18名正常血压者夜间睡眠剥夺对24小时动态血压监测(ABPM)的影响。第一次睡眠剥夺时间为11:00 ~ 7:00,第二次睡眠剥夺时间为2:00 ~ 7:00,间隔一周。主要差异出现在黎明、觉醒前,限制睡眠时SEP和DBP显著降低(P <0.01),恢复睡眠后早晨SEP和HR显著升高(P <0.05)。对这些发现的解释并不明显。我们假设,SEP和DBP在黎明时的减少可能是由于在限制睡眠方案中的睡眠阶段的重组,而SEP和HR在觉醒后的增加可能是由于更大的交感神经激活,好像睡眠剥夺是一种应激状态。
The influence of sleep deprivation during the first part of the night on 24-h ambulatory blood pressure monitoring (ABPM) was studied in 18 normotensive subjects, They underwent two ABPM, one week apart: during the first, they slept from 11 PM to 7 AM, and during the second, from 2 AM to 7 AM. The main differences were observed at dawn, before awakening, when SEP and DBP significantly decreased (P < .01) in the restricted sleep regimen, and during the morning after the recovery sleep, when SEP and HR significantly increased (P < .05). The explanation for these findings is not obvious. We suppose that the decrease in SEP and DBP at dawn might be due to a reorganization of the sleep phases in the restricted sleep regimen, whereas the increase in SEP and HR after awakening might be due to a greater sympathetic activation, as though sleep deprivation was a stressful condition.