Time course of glycogen accumulation after eccentric exercise.
Time course of glycogen accumulation after eccentric exercise.
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离心运动后糖原积累的时间过程。
DOI：
10.1152/jappl.1992.72.5.1999
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发表时间：
1992
影响因子：
3.3
通讯作者：
J J Zachwieja
中科院分区：
文献类型：
--
作者：
J. Widrick;D. Costill;Glenn K. McConell;D. E. Anderson;D. Pearson;J J Zachwieja
这项研究检测了骨骼肌糖原积累的时间进程，这些骨骼肌糖原在同心工作中耗尽，随后受到偏心运动的影响。8名男性在自行车测功机[最大耗氧量(VO2max)的70%]上运动至精疲力竭，并被安排进行碳水化合物限制饮食。大约12小时后，他们通过重复膝关节伸肌的偏心动作来训练一条腿到主观失败，阻力等于他们一次重复的最大同心伸膝力量(ECC腿)的120%。对侧腿不锻炼，作为对照(CON腿)。在72小时的恢复期内，受试者摄入了7g碳水化合物。离心性运动后24~72h，ECC小腿出现中度酸痛。离心运动后即刻，ECC和CON小腿股外侧肌组织的糖原水平相似(分别为40.2+/-5.2和47.6+/-6.4 mmol/kg湿重；P>0.05)。ECC和CON小腿的糖原含量在恢复6h后差异无统计学意义(分别为77.7+/-7.9mmo1/kg湿重和85.1+/-4.9mmo1/kg湿重；P>0.0 5)，但18h后ECC小腿的糖原含量比CON小腿低15%(90.2+/-8.2vs.105.8+/-8.9mmol/kg湿重；P<0.0 5)。恢复72 h后，这一差值增加到24%(115.8+/-8.0vs.153.0+/-12.2mmo1/kg湿重；P<0.05)。这些数据证实，在离心性运动的肌肉中，糖原积累受到了损害。
This study examined the time course of glycogen accumulation in skeletal muscle depleted by concentric work and subsequently subjected to eccentric exercise. Eight men exercised to exhaustion on a cycle ergometer [70% of maximal O2 consumption (VO2max)] and were placed on a carbohydrate-restricted diet. Approximately 12 h later they exercised one leg to subjective failure by repeated eccentric action of the knee extensors against a resistance equal to 120% of their one-repetition maximum concentric knee extension force (ECC leg). The contralateral leg was not exercised and served as a control (CON leg). During the 72-h recovery period, subjects consumed 7 g carbohydrate.kg body wt-1.day-1. Moderate soreness was experienced in the ECC leg 24-72 h after eccentric exercise. Muscle biopsies from the vastus lateralis of the ECC and CON legs revealed similar glycogen levels immediately after eccentric exercise (40.2 +/- 5.2 and 47.6 +/- 6.4 mmol/kg wet wt, respectively; P greater than 0.05). There was no difference in the glycogen content of ECC and CON legs after 6 h of recovery (77.7 +/- 7.9 and 85.1 +/- 4.9 mmol/kg wet wt, respectively; P greater than 0.05), but 18 h later, the ECC leg contained 15% less glycogen than the CON leg (90.2 +/- 8.2 vs. 105.8 +/- 8.9 mmol/kg wet wt; P less than 0.05). After 72 h of recovery, this difference had increased to 24% (115.8 +/- 8.0 vs. 153.0 +/- 12.2 mmol/kg wet wt; P less than 0.05). These data confirm that glycogen accumulation is impaired in eccentrically exercised muscle.(ABSTRACT TRUNCATED AT 250 WORDS)