Indocyanine Green Angiography in Experimental Choroidal Circulatory Disturbance
Indocyanine Green Angiography in Experimental Choroidal Circulatory Disturbance
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DOI：
10.1159/000165916
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发表时间：
2009-01-01
影响因子：
2.1
通讯作者：
Matsumura, M.
中科院分区：
文献类型：
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作者：
Nishikawa, M.;Matsunaga, H.;Matsumura, M.
目的：探讨脉络膜静脉充血对猴吲哚菁绿色血管造影（ICGA）的影响。方法：将5只日本猕猴每只眼的两条涡静脉缝合，并在其出口处烧灼。闭塞后立即进行ICGA和荧光素血管造影（FA）。FA和ICGA结果与组织病理学改变相关。结果如下：ICGA显示在闭塞的涡静脉区域脉络膜动脉充盈延迟，脉络膜静脉以搏动方式逆行充盈。在闭塞区，较大静脉的荧光强度较高。吲哚菁绿色染料的清除延迟约15分钟。组织学检查显示，闭塞区域的脉络膜静脉充血，红细胞增多。结论：脉络膜静脉充血眼的ICGA结果为脉络膜动脉充盈延迟、静脉血流回流、脉络膜静脉荧光强度增加和吲哚菁绿色染料清除延迟。版权所有（C）2008 S. Karger AG，巴塞尔
Purpose: To determine how choroidal venous congestion alters the indocyanine green angiograms (ICGA) of monkeys. Methods: Two vortex veins in each eye of 5 Japanese macaque monkeys were sutured and cauterized at their exit. ICGA and fluorescein angiography (FA) were performed immediately after the occlusions. The FA and ICGA findings were correlated with the histopathological changes. Results: ICGA showed a delay in filling the choroidal arteries in the field of the occluded vortex veins, and the choroidal veins were filled retrogradely in a pulsatile manner. The fluorescence intensity of the larger veins was higher in the occluded area. The clearance of the indocyanine green dye was delayed by approximately 15 min. Histology showed that the choroidal veins in the occluded field were engorged with red blood cells. Conclusion: The ICGA findings in eyes with choroidal venous congestion are a delay in the filling of the choroidal arteries, reflux of venous blood flow, increase in fluorescence intensity of the choroidal veins, and delayed indocyanine green dye clearance. Copyright (C) 2008 S. Karger AG, Basel