The effects of cigarette smoking and alcohol consumption on blood haemoglobin, erythrocytes and leucocytes: a dose related study on male subjects.
The effects of cigarette smoking and alcohol consumption on blood haemoglobin, erythrocytes and leucocytes: a dose related study on male subjects.
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吸烟和饮酒对血红蛋白、红细胞和白细胞的影响：针对男性受试者的剂量相关研究。
DOI：
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发表时间：
1995
期刊：
影响因子：
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通讯作者：
A. Hale
中科院分区：
文献类型：
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作者：
T. Whitehead;D. Robinson;S. Allaway;A. Hale
本研究的目的是量化吸烟和饮酒对血液血红蛋白浓度、红细胞和白细胞的联合剂量相关影响。受试者包括17，670名参加常规健康筛查的男性，平均年龄为43岁，范围为16-91岁。每天吸烟的数量被分为六类，饮酒量被分为七类。在42个不同的吸烟和饮酒组合中，有5个没有报告，因为它们包含的受试者不到30人。每天吸烟超过10支的人血红蛋白浓度显著增加。吸烟也增加了PCV。酒精对Hb和PCV无影响。红细胞计数因饮酒而减少，即使是最低的饮酒量也会产生显着下降。吸烟和饮酒均使MCV呈线性剂量关系升高。吸烟者的白色细胞计数明显增加，即使在每天吸烟10支或更少的受试者中也可观察到。建议在解释血液学值时，应考虑吸烟和饮酒等社会习惯。血液学结果的变化可以用来鼓励更健康的生活方式。
The objective of this study was to quantify the combined dose related effects of cigarette smoking and alcohol consumption on blood haemoglobin concentration, erythrocytes and leucocytes. The subjects consisted of 17,670 males attending for routine health screening, with an average age of 43 years and a range of 16-91 years. The number of cigarettes smoked each day was divided into six categories, and declared alcohol consumption into seven. Of the 42 different combinations of smoking and drinking groups, five were not reported because they contained less than 30 subjects. Haemoglobin concentration was significantly increased in those smoking more than 10 cigarettes per day. Smoking also increased the PCV. Alcohol had no effect on Hb or PCV. The red cell count was reduced by alcohol consumption, with even the lowest consumption producing a significant decrease. Both smoking and drinking raised the MCV in a linear dose relationship. The marked increase in white cell count with smoking was seen even in subjects smoking 10 cigarettes per day or less. It is suggested that social habits such as smoking and drinking should be considered when interpreting blood haematology values. Changes in haematology results could be used to encourage a healthier lifestyle.