SCREENING FOR ALCOHOL-ABUSE USING CAGE SCORES AND LIKELIHOOD RATIOS
SCREENING FOR ALCOHOL-ABUSE USING CAGE SCORES AND LIKELIHOOD RATIOS
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DOI：
10.7326/0003-4819-115-10-774
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发表时间：
1991-11-15
影响因子：
39.2
通讯作者：
LAWTON, MJ
中科院分区：
文献类型：
--
作者：
BUCHSBAUM, DG;BUCHANAN, RG;LAWTON, MJ
目的：评估笼子的表现（缩写为四个问题，请参见下文）问卷调查表，以区分有或没有酒精滥用或依赖性障碍的药物门诊患者。诊断面试时间表的酒精模块和笼子（削减，烦恼，有罪，开眼界）筛查问卷。设置：门诊医疗实践患者：所有18岁以上的患者签署了由大学机构审查委员会批准的同意书的所有患者。计算：计算敏感性，特异性，接收器操作特征（ROC）曲线和笼子的可能性比率分数为0到4.分辨率：样本组的36％符合酒精滥用或依赖史的标准。笼子评分为2或更多，其灵敏度和特异性为74％和91％。 ROC曲线下计算的面积为0.89，而笼子得分的可能性比分别为0.14、1.5、4.5、13和100。这些比率与分别为7％，46％，72％，88％和98％的滥用或依赖障碍的后验概率有关。结论：临床医生可以提高其估计患者酗酒或依赖性风险的能力使用笼子得分的可能性比的障碍。
Objective: To assess the performance of the CAGE (acronym referring to four questions, see below) questionnaire in discriminating between medicine outpatients with and without an alcohol abuse or dependence disorder.Design: A cross-sectional design of a sample of consecutive patients who received both the alcohol module of the diagnostic interview schedule and the CAGE (Cut down, Annoyed, Guilty, Eye-opener) screening questionnaire.Setting: The outpatient medical practice of an urban university teaching hospital.Patients: All patients 18 years or older who signed a consent form approved by the university's institutional review board.Measurement: Calculation of the sensitivity, specificity, receiver operating characteristic (ROC) curve, and likelihood ratio for CAGE Scores of 0 to 4.Results: Thirty-six percent of the sample group met criteria for a history of alcohol abuse or dependence. A CAGE score of 2 or more was associated with a sensitivitY and specificity of 74% and 91%. The calculated area under the ROC curve was 0.89, whereas the likelihood ratios for CAGE scores of 0 to 4 were 0.14, 1.5, 4.5, 13, and 100, respectively. These ratios were associated with posterior probabilities for an abuse or dependence disorder of 7%, 46%, 72%, 88%, and 98%, respectively.Conclusion: Clinicians can improve their ability to estimate a patient's risk for an alcohol abuse or dependence disorder using likelihood ratios for CAGE scores.