EXTRACELLULAR POTENTIALS FROM SINGLE SPINAL MOTONEURONS

EXTRACELLULAR POTENTIALS FROM SINGLE SPINAL MOTONEURONS
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DOI:
10.1085/jgp.42.4.749
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发表时间:
1959-01-01
影响因子:
3.8
通讯作者:
FRANK, K
FRANK, K
中科院分区:
医学2区
文献类型:
--
作者:
FREYGANG, WH;FRANK, K

文献摘要

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在运动神经元表面附近发现的细胞外动作电位与细胞内锋电位有关。证据被引用来支持的假设,即细胞外尖峰有相同的时间过程作为膜电流在网站的记录。同时记录的细胞内和细胞外尖峰进行比较。细胞内的尖峰信号通过一个相当于细胞外记录情况的电路被转换成类似于细胞外出现的瞬变信号。证据表明,录音是从运动神经元的细胞体。结果表明,在细胞外记录位点的膜不产生尖峰,因为细胞外电位的时间过程是由膜的被动特性决定的。
Extracellular action potentials found close to the surface of motoneurons are related to the intracellular spikes. Evidence is cited to support the assumption that the extracellular spikes have the same time course as the membrane current at the site of recording. Simultaneously recorded intracellular and extracellular spikes are compared. Intracellular spikes are transformed, by means of a circuit which is equivalent to the extracellular recording situation, into transients that are like those appearing extra-cellularly. Evidence is given that the recordings are from the cell bodies of motoneurons. The results show that the membrane at the extracellular recording site does not produce a spike since the time course of the extracellular potentials is determined by the passive properties of the membrane.