Speramides A-B, two new prenylated indole alkaloids from the freshwater-derived fungus Aspergillus ochraceus KM007
Speramides A-B, two new prenylated indole alkaloids from the freshwater-derived fungus Aspergillus ochraceus KM007
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Speramides A-B,两种新的异戊二烯化吲哚生物碱,来自淡水源真菌 Aspergillus ochraceus KM007
DOI:
10.1016/j.tetlet.2016.09.071
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发表时间:
2016-11-09
影响因子:
1.8
通讯作者:
Hao, Xiao-Jiang
中科院分区:
文献类型:
--
作者:
Chang, Yao-Wen;Yuan, Chun-Mao;Hao, Xiao-Jiang
Two new prenylated indole alkaloids, named Speramides A (1) and B (2) were isolated from the extraction of the freshwater-derived fungus Aspergillus ochraceus KM007. Their structures were elucidated by means of spectroscopic analysis. Compound 1 is the first prenylated brevianamide derivative. These compounds isolated were evaluated for their antimicrobial activity, among which, compound 1 showed moderate activity against Pseudomonas aeruginosa with a MIC value of 0.8 mu M. (C) 2016 Published by Elsevier Ltd.