METHODS AND PREVALENCE OF NON-INSULIN-DEPENDENT DIABETES-MELLITUS INA BIETHNIC COLORADO POPULATION - THE SAN-LUIS-VALLEY DIABETES STUDY
METHODS AND PREVALENCE OF NON-INSULIN-DEPENDENT DIABETES-MELLITUS INA BIETHNIC COLORADO POPULATION - THE SAN-LUIS-VALLEY DIABETES STUDY
复制标题
DOI：
10.1093/oxfordjournals.aje.a115134
复制
发表时间：
1989-02-01
影响因子：
5
通讯作者：
LEZOTTE, DC
中科院分区：
文献类型：
--
作者：
HAMMAN, RF;MARSHALL, JA;LEZOTTE, DC
圣路易斯谷糖尿病研究旨在确定西班牙裔和盎格鲁裔（非西班牙裔白人）非胰岛素依赖型糖尿病的患病率、危险因素和并发症，采用基于地理的病例对照设计。该研究在科罗拉多州南部的两个县进行，其中 43.6% 是西班牙裔，54.9% 是盎格鲁人。审查医疗实践记录以确定医学诊断的糖尿病患者。没有糖尿病的对照是通过两阶段的家庭随机抽样确定的。糖尿病患者 (n = 343) 和对照组 (n = 607) 前往诊所进行口服葡萄糖耐量试验或当前的降血糖治疗，证实或诊断为非胰岛素依赖型糖尿病。确诊的非胰岛素依赖型糖尿病的年龄调整患病率在英裔男性中为 21/1,000，在西班牙裔男性中为 44/1,000，这是无应答的原因。对于盎格鲁裔女性，患病率为 13/1,000，而西班牙裔女性的患病率为 62/1,000，这是无反应的原因。以前未确诊的非胰岛素依赖型糖尿病在西班牙裔中也较高。西班牙裔男性中确诊的非胰岛素依赖型糖尿病患病率高出 2.1 倍，西班牙裔女性中患病率高出 4.8 倍，这与同类研究报告的西班牙裔非胰岛素依赖型糖尿病患病率高出一致。非胰岛素依赖型糖尿病是西班牙裔人的主要慢性疾病问题。
The San Luis Valley Diabetes Study was undertaken to determine the prevalence, risk factors, and complications of non-insulin-dependent diabetes mellitus in Hispanics and Anglos (non-Hispanic whites), using a geographically based cased-control design. The study was conducted in two southern Colorado counties that include 43.6% Hispanic and 54.9% Anglo persons. Medical practice records were reviewed to identify medically diagnosed diabetics. Controls without diabetes were identified by a two-stage random sample of households. Diabetics (n = 343) and controls (n = 607) attended a clinic where and oral glucose tolerance test or current hypoglycemic therapy confirmed or diagnosed non-insulin-dependent diabetes mellitus. The age-adjusted prevalence of confirmed non-insulin-dependent diabetes mellitus was 21/1,000 in Anglo males and 44/1,000 in Hispanic males, accounting for non-response. For Anglo females, the prevalence was 13/1,000 compared with 62/1,000 for Hispanic females, accounting for nonresponse. Previously undiagnosed non-insulin-dependent diabetes mellitus was also higher among Hispanics. There was a 2.1-fold excess of confirmed non-insulin-dependent diabetes mellitus among Hispanic males and a 4.8-fold excess among Hispanic females, consistent with the excess non-insulin-dependent diabetes mellitus Hispanics reported from comparable studies. Non-insulin-dependent diabetes mellitus is a major chronic disease problem for persons of Hispanic ethnicity.