Vertebral fracture assessment: Enhancing the diagnosis, prevention, and treatment of osteoporosis.
Vertebral fracture assessment: Enhancing the diagnosis, prevention, and treatment of osteoporosis.
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DOI：
10.1016/j.bone.2017.03.004
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发表时间：
2017-11
期刊：
影响因子：
4.1
通讯作者：
Meltem Zeytinoglu;R. Jain;T. Vokes
中科院分区：
文献类型：
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作者：
Meltem Zeytinoglu;R. Jain;T. Vokes
骨质疏松症是一种非常普遍的疾病，导致显著的发病率和死亡率。然而，它往往是未经治疗的。椎骨骨折通常不会引起临床关注，然而，它们的存在是骨质疏松症的诊断，有助于预测未来骨折的风险，并可能改变药物治疗的选择。将脊柱侧位成像技术添加到密度计中，用于椎骨骨折评估（VFA），代表了诊断椎骨骨折和骨质疏松症能力的重大进步。VFA是一种未充分利用的高效成像工具，可增强骨质疏松症检测和骨折预防。几个因素使VFA成为评价椎体骨折的理想技术。其中包括：在骨密度测量的同时获得图像的能力，与脊柱放射摄影相比，具有显著更低的辐射暴露，并且成本更低。本文综述了识别椎体骨折的临床意义、VFA的起源、临床适应证、诊断椎体骨折的方法、VFA的解释以及该技术的优点和局限性。
Osteoporosis is a highly prevalent condition, resulting in significant morbidity and mortality. Nevertheless, it is frequently untreated. Vertebral fractures often do not come to clinical attention, yet, their presence is diagnostic of osteoporosis, helps to predict the risk of future fractures, and may alter the choice of pharmacotherapy. The addition of lateral spine imaging technology to the densitometer, for vertebral fracture assessment (VFA), represented a major advancement in the ability to diagnose vertebral fractures and osteoporosis. VFA is an under-utilized and highly effective imaging tool to enhance osteoporosis detection and fracture prevention. Several factors make VFA an ideal technology to evaluate for vertebral fractures. These include: the ability to obtain the image at the same time the bone density is done, with significantly lower radiation exposure than with spine radiography, and at a lower cost. This review provides an overview of the clinical significance of identifying vertebral fractures, the origins of the VFA, its clinical indications, a review of the methods used to diagnose vertebral fracture, an overview on interpreting the VFA, and the strengths and limitations of this technique.