Chronic Obstructive Pulmonary Disease in America's Black Population
Chronic Obstructive Pulmonary Disease in America's Black Population
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DOI：
10.1164/rccm.201810-1909pp
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发表时间：
2019-08-15
影响因子：
24.7
通讯作者：
Han, MeiLan K.
中科院分区：
文献类型：
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作者：
Ejike, Chinedu O.;Dransfield, Mark T.;Han, MeiLan K.
慢性阻塞性肺疾病 (COPD) 是一种进行性、使人衰弱的呼吸系统疾病，目前是美国第三大死亡原因 (1)。尽管超过 1100 万人被诊断患有慢性阻塞性肺病，但还有更多人患有未确诊的疾病 (1)。随着美国人口老龄化，这一数字预计将进一步增加。慢性阻塞性肺病越来越被认为是美国多元文化黑人群体中的一个主要健康问题。直到最近招募了大量黑人个体的 COPDGene（慢性阻塞性肺病流行病学遗传学研究）(2) 等研究之前，美国还没有太多的慢性阻塞性肺病研究纳入足够多的黑人群体，以了解该疾病如何影响黑人群体或在黑人群体中可能存在差异。此外，有证据表明，美国出生的黑人与黑人移民之间的慢性阻塞性肺病患病率和发病率差异很大。这引发了对当前知识有效性的质疑，在大多数研究中，当前知识在很大程度上将所有“美国黑人”视为同质的“非裔美国人”。这一假设忽略了美国黑人在社会经济地位、烟草或生物质烟雾暴露、行为、获得医疗保健的机会、健康保险覆盖范围和疾病管理方面的差异。在这篇肺部观点文章中，我们定义了美国黑人人口，并研究了美国黑人中慢性阻塞性肺病的患病率、危险因素、发病率和死亡率。
Chronic obstructive pulmonary disease (COPD) is a progressive, debilitating respiratory condition and currently the third leading cause of death in the United States (1). Though over 11 million people have been diagnosed with COPD, many more have undiagnosed disease (1). This number is projected to increase further as America’s population ages. COPD is increasingly being recognized as a major health problem in America’s multicultural black population. Until recent studies such as COPDGene (Genetic Study of the Epidemiology of COPD)(2), which recruited a significant number of black individuals, there have not been many COPD studies inclusive enough of the black population in America to understand how the disease affects or may differ in the black population. Furthermore, evidence indicates that the prevalence and morbidity of COPD vary widely among US-born black individuals versus black immigrants. This brings into question the validity of current knowledge, which largely refers to all “US blacks” as a homogeneous “African American” populace in a majority of studies. This assumption ignores the variations in socioeconomic status, tobacco or biomass smoke exposure, behaviors, access to health care, health insurance coverage, and disease management among black individuals in America. In this pulmonary perspective article, we define America’s black population and examine the prevalence, risk factors, morbidity, and mortality attributed to COPD among black individuals in