Self-Assembling Supramolecular Hybrid Hydrogel Beads
Self-Assembling Supramolecular Hybrid Hydrogel Beads
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自组装超分子杂化水凝胶珠
DOI：
10.1002/ange.201911404
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发表时间：
2019
影响因子：
--
通讯作者：
Piras C
中科院分区：
文献类型：
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作者：
Piras C
为了在超分子凝胶上施加形状和结构，我们将低分子量胶凝剂（LMWG）与聚合物胶凝剂（PG）藻酸钙在混合水凝胶中结合联合收割机。通过对正交凝胶化方法进行热和时间控制，该系统形成了一个扩展的互穿网络或核-壳结构的凝胶珠-一个罕见的在离散凝胶球内配制的超分子凝胶的例子。自组装的LMWG在珠粒中保留了其独特的性质，例如修复PdII并原位还原它以产生催化活性Pd 0纳米颗粒。 单个负载PdNP的凝胶珠可以催化Suzuki-Miyaura反应，构成简单且易于使用的反应给药形式。这些形状和结构独特的LMWG填充凝胶珠是一种多功能平台技术，在一系列应用中具有巨大潜力。
With the goal of imposing shape and structure on supramolecular gels, we combine a low‐molecular‐weight gelator (LMWG) with the polymer gelator (PG) calcium alginate in a hybrid hydrogel. By imposing thermal and temporal control of the orthogonal gelation methods, the system either forms an extended interpenetrating network or core–shell‐structured gel beads—a rare example of a supramolecular gel formulated inside discrete gel spheres. The self‐assembled LMWG retains its unique properties within the beads, such as remediating PdIIand reducing it in situ to yield catalytically active Pd0nanoparticles. A single PdNP‐loaded gel bead can catalyse the Suzuki–Miyaura reaction, constituting a simple and easy‐to‐use reaction‐dosing form. These uniquely shaped and structured LMWG‐filled gel beads are a versatile platform technology with great potential in a range of applications.