Impact of COVID-19 lockdown on glycemic control in patients with type 1 diabetes
Impact of COVID-19 lockdown on glycemic control in patients with type 1 diabetes
复制标题
DOI：
10.1016/j.diabres.2020.108348
复制
发表时间：
2020-08-01
影响因子：
5.1
通讯作者：
Bellido, Virginia
中科院分区：
文献类型：
--
作者：
Fernandez, Elsa;Cortazar, Alicia;Bellido, Virginia
简介：COVID-19 大流行迫使各国政府采取特殊措施，以最大限度地减少其传播，实施封锁政策。本研究的目的是评估封锁对 1 型糖尿病 (T1D) 血糖控制的影响。材料和方法：纳入使用快速血糖监测的 T1D 患者。将封锁前 14 天的数据与封锁 8 周后最后 14 天的数据进行比较。结果：总共纳入 307 名患者（年龄 45.8 +/- 12.6 岁，50.2% 男性，糖尿病病程 21.1 +/- 12.3 年）。只有一名患者感染了 COVID-19。平均血糖从 166.89 +/- 29.4 下降至 158.0 +/- 29.0 mg/dL，估计 HbA1c 从 7.4 +/- 1.0 下降至 7.1 +/- 1.0%（54 +/- 10.9 vs 57 +/- 10.9 mmol/mol；p < 0.001）。范围内的时间从 57.8 +/- 15.8 增加到 62.46 +/- 16.1%。高血糖180 mg/dL和>250 mg/dL的时间分别从37.3 +/- 1.9%减少到32.0 +/- 17.1%，从13.0 +/- 11.3减少到10.3 +/- 10.6%； （p < 0.001）。低血糖时间
Introduction: The COVID-19 pandemic has forced governments to take exceptional measures to minimize its spread, imposing lockdown policies. The aim of this study was to evaluate the impact of lockdown on type 1 diabetes (T1D) glycemic control.Material and methods: People with T1D using flash glucose monitoring were included. Data from the 14 days before lockdown were compared with data from the last 14 days after 8 weeks of lockdown.Results: A total of 307 patients were included (age 45.8 +/- 12.6 years, 50.2% male, diabetes duration 21.1 +/- 12.3 years). Only one patient had COVID-19 infection.Mean glucose decreased from 166.89 +/- 29.4 to 158.0 +/- 29.0 mg/dL and estimated HbA1c declined from 7.4 +/- 1.0 to 7.1 +/- 1.0% (54 +/- 10.9 vs 57 +/- 10.9 mmol/mol; p 0.001). Time in range increased from 57.8 +/- 15.8 to 62.46 +/- 16.1%. Time in hyperglycemia 180 mg/dL and >250 mg/dL decreased from 37.3 +/- 1.9% to 32.0 +/- 17.1% and from 13.0 +/- 11.3 to 10.3 +/- 10.6%, respectively; (p < 0.001). Time in hypoglycaemia