Fractal analysis of radiographs: Assessment of trabecular bone structure and prediction of elastic modulus and strength
Fractal analysis of radiographs: Assessment of trabecular bone structure and prediction of elastic modulus and strength
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DOI：
10.1118/1.598628
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发表时间：
1999-07-01
期刊：
影响因子：
3.8
通讯作者：
Genant, H
中科院分区：
文献类型：
--
作者：
Majumdar, S;Lin, J;Genant, H
本研究的目的是确定X光片的分形维数是否提供与骨矿物质密度（BMD）和骨生物力学相关的骨小梁结构的测量，以及这些关系是否依赖于用于计算分形维数的技术。从椎骨和股骨获得了87个立方形的人松质骨标本。对立方体进行沿着所有三个方向-上-下（SI）、内侧-外侧（ML）和前-后（AP）的射线照相，数字化，校正背景变化，并应用基于分形的技术来量化小梁结构。三种不同的技术，即，半方差，表面积，功率谱方法。沿沿着三个方向对试样进行压缩测试，并测定杨氏模量（YM）。沿SI方向沿着测量抗压强度。采用定量计算机断层扫描测量骨小梁BMD。高分辨率磁共振图像用于获得骨小梁结构的三维测量，如表观骨体积分数、骨小梁厚度、间距和数量。不同方向计算的骨小梁结构测量值差异有显著性（p
The purpose of this study was to determine whether fractal dimension of radiographs provide measures of trabecular bone structure which correlate with bone mineral density (BMD) and bane biomechanics, and whether these relationships depend on the technique used to calculate the fractal dimension. Eighty seven cubic specimen of human trabecular bone were obtained from the vertebrae and femur. The cubes were radiographed along all three orientations-superior-inferior (SI), medial-lateral (ML), and anterior-posterior (AP), digitized, corrected for background variations, and fractal based techniques were applied to quantify trabecular structure. Three different techniques namely, semivariance, surface area, and power spectral methods were used. The specimens were tested in compression along three orientations and the Young's modulus-(YM) was determined. Compressive strength was measured along the SI direction. Quantitative computed tomography was used to measure trabecular BMD. High-resolution magnetic-resonance images were used to obtain three-dimensional measures of trabecular architecture such as the apparent bone volume fraction, trabecular thickness, spacing, and number. The measures of trabecular structure computed in the different directions showed significant differences (p