Genetics of bipolar disorder
Genetics of bipolar disorder
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DOI：
10.1093/med/9780198713005.003.0070
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发表时间：
2020-03
期刊：
影响因子：
--
通讯作者：
F. McMahon;S. Detera-Wadleigh
中科院分区：
文献类型：
--
作者：
F. McMahon;S. Detera-Wadleigh
双相情感障碍代表了最高度遗传的一组常见精神疾病，但这些疾病的复杂遗传基础最近才开始揭示自己。本章回顾了遗传流行病学，分子遗传学，双相情感障碍的遗传模型研究。本章的结论与相关的临床护理的预期发展的一瞥，并预计一些未来的研究方向。
Bipolar disorder represents one of the most highly heritable group of common psychiatric disorders, but the complex genetic basis of these disorders has only recently begun to reveal itself. This chapter reviews the genetic epidemiology, molecular genetics, and genetic modelling studies of bipolar disorder. The chapter concludes with a glimpse of anticipated developments of relevance to clinical care and anticipates some future research directions.