Benign solitary solid cold thyroid nodules:: US-guided interstitial laser photocoagulation -: Initial experience
Benign solitary solid cold thyroid nodules:: US-guided interstitial laser photocoagulation -: Initial experience
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DOI：
10.1148/radiol.2251011042
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发表时间：
2002-10-01
期刊：
影响因子：
19.7
通讯作者：
Hegedüs, L
中科院分区：
文献类型：
--
作者：
Dossing, H;Bennedbæk, FN;Hegedüs, L
目的：评估超声检查 (US) 引导间质激光光凝术 (ILP) 对良性孤立性甲状腺冷结节体积和任何结节相关症状的影响。 材料和方法：对 16 例甲状腺功能正常且甲状腺良性结节患者进行了 ILP。所有患者均未接受放射性核素扫描。患者接受了一次 ILP 治疗。在超声引导下将一根针放置在甲状腺结节中，并将激光光纤放置在针的管腔中。患者接受 287-1,200 秒的治疗，输出功率为 1-3 W。ILP 在连续 US 指导下进行，并在生态变化稳定时终止。治疗前及治疗后1、3、6个月评估甲状腺结节体积和甲状腺功能。同期，对 15 名未经治疗的患者（对照组）进行了随访，以评估未经治疗的甲状腺结节的大小。 结果：在接受 ILP 治疗的 16 名患者中，6 个月后平均甲状腺结节体积从 10 mL 减少至 5.4 mL（P < .001）。给出的中位能量为 761 J。给出的热能剂量与结节减少之间没有关系。 6 个月后压力症状显着减轻 (P = .0002)。所有患者对治疗的耐受性良好。对照组甲状腺结节体积未见显着变化。结论：超声引导下的 ILP 可能成为治疗不能或不愿接受手术的良性孤立性实性冷甲状腺结节的有效非手术替代方案。 (C) 北美放射学会，2002 年。
PURPOSE: To evaluate the effects of ultrasonography (US)-guided interstitial laser photocoagulation (ILP) on the volume of benign solitary solid cold thyroid nodules and any nodule-related symptoms.MATERIALS AND METHODS: ILP was performed in 16 patients with normal thyroid function and a solid benign thyroid nodule. None of the patients had uptake on a radionuclide scan. Patients underwent one ILP session. A needle was positioned in the thyroid nodule with US guidance, and the laser fiber was placed in the lumen of the needle. Patients were treated for 287-1,200 seconds with an output power of 1-3 W. ILP was performed with continuous US guidance and terminated when the ecogenic changes were stationary. Thyroid nodule volume and thyroid function were evaluated before and 1, 3, and 6 months after treatment. During the same period, 15 untreated patients (control group) were followed up to evaluate the size of the untreated thyroid nodule.RESULTS: In the 16 patients treated with ILP, the mean thyroid nodule volume decreased from 10 to 5.4 mL (P < .001) after 6 months. The median energy given was 761 J. There was no relationship between the dose of thermal energy given and nodule reduction. Pressure symptoms were significantly reduced (P = .0002) after 6 months. The treatment was well-tolerated in all patients. No significant change in thyroid nodule volume was seen in the control group.CONCLUSION: US-guided ILP could become a useful nonsurgical alternative in the treatment of the benign solitary solid cold thyroid nodule in patients who cannot or will not undergo surgery. (C) RSNA, 2002.