THE ROLE OF MUSCLE MASS IN THE CARDIOVASCULAR-RESPONSE TO STATIC CONTRACTIONS
THE ROLE OF MUSCLE MASS IN THE CARDIOVASCULAR-RESPONSE TO STATIC CONTRACTIONS
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DOI：
10.1113/jphysiol.1980.sp013492
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发表时间：
1980-01-01
影响因子：
5.5
通讯作者：
SCHIBYE, B
中科院分区：
文献类型：
--
作者：
MITCHELL, JH;PAYNE, FC;SCHIBYE, B
男性（11人）用手指（手指II和III）、前臂（手柄）和膝伸肌（膝角90 °）进行静态收缩。在40%最大随意收缩（MVC）2分钟。在7名受试者的手握和膝关节伸展相结合，两个收缩保持在40%MVC。在收缩结束时，将袖带在收缩的肢体周围充气至250 mmHg持续3 min。在收缩前和收缩期间以及恢复期间，在袖带充气和不充气的情况下，对力、心率和动脉内血压（肱动脉;近端20 cm）进行连续测量。心率和血压随着收缩的开始而暂时升高，随后逐渐进一步升高。这种反应模式对于所有研究的肌肉群都是相似的。在收缩过程中增加的顺序是：手指，前臂，膝伸肌和前臂-膝联合伸肌，每个肌肉群之间的差异是显着的。在袖带充气收缩的恢复期，心率恢复至对照水平。血压下降，但仍高于收缩前水平，直到袖带释放。目前的数据不同意与早期的观察表明，心血管反应的静态收缩是成比例的% MVC，无论涉及的肌肉质量的收缩。这些研究结果与传统的概念，中枢和外周神经输入参与心血管调节运动，与中央和外周因素有关的质量的肌肉从事的运动。
Men (11) performed static contractions with the fingers (digits II and III), forearm (handgrip) and the knee extensors (knee angle 90.degree.) at 40% maximal voluntary contraction (MVC) for 2 min. In 7 of the subjects handgrip and knee extension were combined, both contractions held at 40% MVC. At the end of the contraction, cuffs were inflated to 250 mmHg for 3 min around the extremity which was contracting. Continuous measurements were performed of force, heart rate and intra-arterial blood pressure (a [arteria] brachialis; 20 cm proximally), before and during contraction and during recovery with and without cuffs inflated. Heart rate and blood pressure increased momentarily with the onset of a contraction whereafter a gradual further increase took place. This pattern of response was similar for all muscle groups studied. The increases during the contractions were in the order: fingers, forearm, knee extensors and combined forearm-knee extensors, with the difference between each muscle group contraction being significant. In the recovery period from a contraction with the cuff(s) inflated, heart rate returned to control level. Blood pressure dropped, but remained elevated above pre-contraction level until the cuff(s) was released. The present data disagrees with earlier observations showing that the cardiovascular response to a static contraction is proportional to the % MVC regardless of the muscle mass involved in the contraction. These findings are in line with the traditional concept of central and peripheral nervous inputs involved in the cardiovascular adjustments to exercise, with the central and the peripheral factors being related to the mass of the muscles engaged in the exercise.