Reduced platelet adhesion and improved corrosion resistance of superhydrophobic TiO2-nanotube-coated 316L stainless steel
Reduced platelet adhesion and improved corrosion resistance of superhydrophobic TiO2-nanotube-coated 316L stainless steel
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DOI：
10.1016/j.colsurfb.2014.11.028
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发表时间：
2015-01-01
影响因子：
5.8
通讯作者：
Vogler, Erwin A.
中科院分区：
文献类型：
--
作者：
Huang, Qiaoling;Yang, Yun;Vogler, Erwin A.
为提高不锈钢的耐蚀性和血液相容性，在316L不锈钢表面制备了超亲水和超疏水的二氧化钛纳米管阵列。通过电化学阳极氧化在不锈钢表面沉积钛膜，在不锈钢表面制备出垂直排列的超亲水非晶态TNTs。通过焙烧诱导出锐钛矿相(超亲水)，并通过氟硅烷化将超亲水转变为超疏水。用扫描电子显微镜、X射线衍射仪、X射线光电子能谱和接触角测角仪对样品的形貌、结构和表面润湿性进行了表征。研究了表面润湿性对其耐蚀性和片层粘附性的影响。结果表明，晶相(锐钛矿相与非晶相)和润湿性对耐蚀性和片层粘附性有很大影响。超亲水的非晶态TNTs不能保护SS免受腐蚀，而超疏水的非晶态TNTs略有提高SS的耐蚀性。超亲水和超疏水锐钛矿型TNTs均显著提高了不锈钢的耐蚀性能。超亲水的无定形TNTs减少了血小板的黏附和活化，而超亲水的锐钛矿型TNTs则激活了纤维蛋白网络的形成。相反，两种超疏水TNTs(超疏水无定形TNTs和超疏水锐钛矿型TNTs)都显著减少了血小板的粘附性，并提高了耐腐蚀性，无论是哪种晶相。SS表面的超疏水锐钛矿型TNTs涂层为SS作为一种永久性生物材料在血液接触生物医疗设备中的应用提供了机会，可以有效地结合减少血小板的黏附/激活和提高耐腐蚀性。(C)2014爱思唯尔B.V.保留所有权利。
Superhydrophilic and superhydrophobic TiO2 nanotube (TNT) arrays were fabricated on 316L stainless steel (SS) to improve corrosion resistance and hemocompatibility of SS. Vertically-aligned superhydrophilic amorphous TNTs were fabricated on SS by electrochemical anodization of Ti films deposited on SS. Calcination was carried out to induce anatase phase (superhydrophilic), and fluorosilanization was used to convert superhydrophilicity to superhydrophobicity. The morphology, structure and surface wettability of the samples were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and contact angle goniometry. The effects of surface wettability on corrosion resistance and platelet adhesion were investigated. The results showed that crystalline phase (anatase vs. amorphous) and wettability strongly affected corrosion resistance and platelet adhesion. The superhydrophilic amorphous TNTs failed to protect SS from corrosion whereas superhydrophobic amorphous TNTs slightly improved corrosion resistance of SS. Both superhydrophilic and superhydrophobic anatase TNTs significantly improved corrosion resistance of SS. The superhydrophilic amorphous TNTs minimized platelet adhesion and activation whereas superhydrophilic anatase TNTs activated the formation of fibrin network. On the contrary, both superhydrophobic TNTs (superhydrophobic amorphous TNTs and superhydrophobic anatase TNTs) reduced platelet adhesion significantly and improved corrosion resistance regardless of crystalline phase. Superhydrophobic anatase TNTs coating on SS surface offers the opportunity for the application of SS as a promising permanent biomaterial in blood contacting biomedical devices, where both reducing platelets adhesion/activation and improving corrosion resistance can be effectively combined. (C) 2014 Elsevier B.V. All rights reserved.