Usefulness of magnifying endoscopy in the diagnosis of early gastric cancer
Usefulness of magnifying endoscopy in the diagnosis of early gastric cancer
复制标题
DOI：
10.1055/s-2004-814184
复制
发表时间：
2004-02-01
期刊：
影响因子：
9.3
通讯作者：
Goto, H
中科院分区：
文献类型：
--
作者：
Otsuka, Y;Niwa, Y;Goto, H
背景和研究目的：我们调查了早期胃癌的特征性发现揭示放大内镜，并澄清其与组织病理学features.Patients和方法的关系：共74例早期胃癌患者进行了放大内镜（x 80）2000年3月至2001年12月。内镜检查示隆起型癌11例，凹陷型癌63例，组织学检查示分化型癌56例，未分化型癌18例。组织病理学结果进行了比较，从放大内镜的结果关于微小的表面结构和microvessels.Results：我们能够大致分类的微小的表面结构的早期胃癌放大内镜所示的三种模式，如下：（一）一个小的规则模式的沟和脊;（二）一个不规则的模式的沟和脊;和（三）缺乏可见的结构。根据不规则的微小血管和血管口径的变化，将在癌性病变中观察到的异常微血管分为两种类型。小规则型的沟嵴在分化癌中的出现率（30/56，53.6%）明显高于未分化癌（2/18，11.1%）。未分化癌组织中可见微小结构和不规则微血管的比例（44.4%和77.7%）明显高于分化癌组织（5.4%和51.8%）。放大内镜对早期胃癌的诊断有一定的预测价值。
Background and Study Aims: We investigated the characteristic findings of early gastric cancer revealed by magnifying endoscopy, and clarified their relationship with histopathological features.Patients and Methods: A total of 74 patients with early gastric cancer underwent magnifying endoscopy ( x 80) between March 2000 and December 2001. The endoscopic findings demonstrated 11 elevated-type carcinomas and 63 depressed-type, and histological examination showed 56 differentiated carcinomas and 18 undifferentiated carcinomas. The histopathological results were compared with findings from magnifying endoscopy regarding minute surface structure and microvessels.Results: We were able to roughly classify the minute surface structure of early gastric cancer as shown by magnifying endoscopy into three patterns, as follows: (i) a small regular pattern of sulci and ridges; (ii) an irregular pattern of sulci and ridges; and (iii) a lack of visible structure. Abnormal microvessels observed in cancerous lesions were classified according to two patterns: irregular minute vessels and variation of vessel caliber. The small regular pattern of sulci and ridges was significantly more frequently observed in differentiated carcinoma (30/56, 53.6%) than in undifferentiated carcinoma (2/18, 11.1%). Lack of visible structure and irregular minute vessels were significantly more frequently observed in undifferentiated carcinoma (44.4% and 77.7%) than in differentiated carcinomas (5.4% and 51.8%).Conclusion: The minute surface structure and microvessels observed by magnifying endoscopy were related to histopathological findings. Magnifying endoscopy is valuable for predicting the histological nature in the diagnosis of early gastric cancer.