Which is the best indicator of muscle oxygen extraction during exercise using NIRS? -EVidence that HHb is not the candidate
Which is the best indicator of muscle oxygen extraction during exercise using NIRS? -EVidence that HHb is not the candidate
复制标题
使用 NIRS 运动期间肌肉吸氧量的最佳指标是什么？
DOI：
10.1007/978-1-4614-7411-1_23
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发表时间：
2013
影响因子：
--
通讯作者：
Katsumura T.
中科院分区：
文献类型：
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作者：
Kime R;Fujioka M;Osawa T;Takagi S;Niwayama M;Kaneko Y;Osada T;Murase N;Katsumura T.
近年来，脱氧血红蛋白（deoxygenated hemoglobin，HHb）作为运动时肌肉氧摄取的最常用指标之一，在运动生理学领域得到了广泛的应用。然而，HHb可能不足以代表肌肉O2提取，因为总血红蛋白（tHb）在运动期间不稳定。本研究的目的是测量周期运动中各种肌肉氧合信号，并阐明哪一种是运动过程中肌肉氧提取的最佳指标。10名健康男性进行了6分钟的周期运动在中度和重度的工作率。氧合血红蛋白（O2-Hb），HHb，tHb，和肌肉组织氧饱和度（SmO2）的测量与近红外空间分辨光谱从股外侧肌。还在靠近NIRS探头的部位监测皮肤血流量（sBF）。在中等强度运动期间，tHb、O2-Hb和SmO2呈进行性升高，直至运动结束。相反，HHb在中等工作率期间保持稳定。sBF在中等强度运动时保持稳定，但在高强度运动时逐渐下降。这些结果提供的证据表明，HHb可能不足以代表肌肉O2提取，因为tHb是不稳定的运动过程中，HHb是不敏感的运动引起的充血。
Recently, deoxygenated hemoglobin (HHb) has been used as one of the most popular indicators of muscle O2extraction during exercise in the field of exercise physiology. However, HHb may not sufficiently represent muscle O2extraction, as total hemoglobin (tHb) is not stable during exercise. The purpose of this study was to measure various muscle oxygenation signals during cycle exercise and clarify which is the best indicator of muscle O2extraction during exercise using NIRS. Ten healthy men performed 6-min cycle exercise at both moderate and heavy work rates. Oxygenated hemoglobin (O2-Hb), HHb, tHb, and muscle tissue oxygen saturation (SmO2) were measured with near-infrared spatial resolved spectroscopy from the vastus lateralis muscle. Skin blood flow (sBF) was also monitored at a site close to the NIRS probe. During moderate exercise, tHb, O2-Hb, and SmO2displayed progressive increases until the end of exercise. In contrast, HHb remained stable during moderate work rate. sBF remained stable during moderate exercise but showed a progressive decrease at heavy work rate. These results provide evidence that HHb may not sufficiently represent muscle O2extraction since tHb is not stable during exercise and HHb is insensitive to exercise-induced hyperaemia.