Time-Dependent Hydrogen Bond Network Formation in Glycerol-Based Deep Eutectic Solvents.
Time-Dependent Hydrogen Bond Network Formation in Glycerol-Based Deep Eutectic Solvents.
复制标题
DOI：
10.1002/cphc.202100806
复制
发表时间：
2022-04
期刊：
影响因子：
--
通讯作者：
K. Dziubinska-Kühn;Marion Pupier;J. Matysik;Jasmine Viger‐Gravel;B. Karg;M. Kowalska
中科院分区：
文献类型：
--
作者：
K. Dziubinska-Kühn;Marion Pupier;J. Matysik;Jasmine Viger‐Gravel;B. Karg;M. Kowalska
在过去的几年中，由于其可行的合成和整体低的生产成本，深Eu 3+溶剂作为一类新型的绿色溶剂而受到欢迎。甘油（Gly）基深度共沸溶剂的性质通常与扩展的氢键网络的形成有关。在这项研究中，二维核磁共振（NMR）光谱分析的影响，甘油过饱和的氢键受体，氯化胆碱（ChCl）上的甘氨酸（摩尔比1：2氯化胆碱：甘氨酸）的结构排列，选择代表甘氨酸为基础的深Euronectin溶剂。甘油分子的重排，另外捕获水分子内的孤立的集群，揭示了在时间分辨分析，在存在下的各种馏分的水添加到溶剂中进行。基于所揭示的甘油-水相互作用，发现200%过饱和的深Eurobenzene溶剂（1：4 ChCl：Gly）是合适的冷冻保护剂候选物。
Over the last few years, Deep Eutectic Solvents have gained popularity as a novel class of green solvents, due to their feasible synthesis and overall low production costs. The properties of glycerol (Gly)-based Deep Eutectic Solvents are frequently associated with the formation of an extended hydrogen bond network. In this study, two-dimensional Nuclear Magnetic Resonance (NMR) spectroscopy is employed to analyse the effect of glycerol oversaturation of the hydrogen bond acceptor, choline chloride (ChCl) on the structural arrangement of glyceline (molar ratio 1 : 2 ChCl:Gly), selected to represent Gly-based Deep Eutectic Solvents. The rearrangement of glycerol molecules, additionally trapping water molecules inside of isolated clusters, is revealed during a time-resolved analysis, performed in the presence of various fractions of water added to solvent. 200 % oversaturated Deep Eutectic Solvent (1 : 4 ChCl:Gly) is found to be a suitable cryoprotectant candidate, based on the revealed glycerol-water interactions.