Overdiagnosis of Thyroid Cancer: Answers to Five Key Questions
Overdiagnosis of Thyroid Cancer: Answers to Five Key Questions
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DOI：
10.1016/j.acra.2015.01.019
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发表时间：
2015-08-01
影响因子：
4.8
通讯作者：
Davies, Louise
中科院分区：
文献类型：
--
作者：
Hoang, Jenny K.;Nguyen, Xuan V.;Davies, Louise
甲状腺癌通过具有惰性癌症库和导致从库中诊断出偶发癌症的实践模式来满足过度诊断的标准。基于人群的数据也支持了过度诊断的发生，该数据显示甲状腺癌发病率惊人上升，而死亡率没有变化。由于导致过度诊断的活动之一是对影像学中偶然发现的甲状腺结节进行检查，因此放射科医生了解过度诊断的问题及其在问题和解决方案中的作用至关重要。本文讨论了 1) 甲状腺癌的基本事实，2) 支持过度诊断的证据，3) 放射学在过度诊断中的作用，4) 过度诊断的危害，以及 5) 放射科医生可以采取的尽量减少问题的步骤。
Thyroid cancer fulfills the criteria for overdiagnosis by having a reservoir of indolent cancers and practice patterns leading to the diagnosis of incidental cancers from the reservoir. The occurrence of overdiagnosis is also supported by population-based data showing an alarming rise in thyroid cancer incidence without change in mortality. Because one of the activities leading to overdiagnosis is the workup of incidental thyroid nodules detected on imaging, it is critical that radiologists understand the issue of overdiagnosis and their role in the problem and solution. This article-addresses 1) essential thyroid cancer facts, 2) the evidence supporting overdiagnosis, 3) the role of radiology in overdiagnosis, 4) harms of overdiagnosis, and 5) steps radiologists can take to minimize the problem.