Allergic symptoms and microflora in schoolchildren

Allergic symptoms and microflora in schoolchildren
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DOI:
10.1016/j.jadohealth.2003.09.018
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发表时间:
2004-08-01
影响因子:
7.6
通讯作者:
Shirakawa, T
Shirakawa, T
中科院分区:
医学2区
文献类型:
--
作者:
Fukuda, S;Ishikawa, H;Shirakawa, T

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我们研究了867名初中儿童,并进行了问卷调查,记录过敏症状和环境变量,并测量了血清免疫球蛋白E水平和血清抗体的免疫球蛋白G滴度的微生物菌群。共有716名受试者最终用于统计;具有以下过敏症状中至少两种的受试者:哮喘、鼻炎、湿疹或食物过敏,对普通拟杆菌的IgG滴度显著高于其他组。这一发现表明,一种拟杆菌属的肠道微生物。往往会影响肠道问题,但需要进一步的研究来澄清这一点。(C)青少年医学协会,2004年。
We studied 867 junior high school children and administered a questionnaire documenting allergic symptoms and environmental variables, and measured Immunoglobulin E serum levels and the immunoglobulin G titers of serum antibody to microflora. A total of 716 subjects were ultimately used for statistics; those with at least two of the following allergic symptoms: asthma, rhinitis, eczema, or food allergy, showed significantly higher IgG titers to Bactroides vulgatus than other groups. This finding suggests that a species of the Bacteroides genus of the intestinal microflora. tends to affect the gut issues, but further studies are needed to clarify this. (C) Society for Adolescent Medicine, 2004.