Proceedings from an international consensus meeting on posttransplantation diabetes mellitus: recommendations and future directions.

Proceedings from an international consensus meeting on posttransplantation diabetes mellitus: recommendations and future directions.
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DOI:
10.1111/ajt.12850
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发表时间:
2014-09
期刊:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
影响因子:
--
通讯作者:
Säemann MD
Säemann MD
中科院分区:
其他
文献类型:
--
作者:
Sharif A;Hecking M;de Vries AP;Porrini E;Hornum M;Rasoul-Rockenschaub S;Berlakovich G;Krebs M;Kautzky-Willer A;Schernthaner G;Marchetti P;Pacini G;Ojo A;Takahara S;Larsen JL;Budde K;Eller K;Pascual J;Jardine A;Bakker SJ;Valderhaug TG;Jenssen TG;Cohney S;Säemann MD

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2013年9月8-9日在维也纳举行了一次共识会议,讨论移植后糖尿病发展的诊断和治疗挑战。国际专家小组由24名移植肾学家、外科医生、糖尿病学家和临床科学家组成,他们开会的目的是根据新出现的临床数据和研究审查以前的指南。本文提供了协商一致讨论的建议。虽然会议以肾脏为中心,反映了目前的专业知识,但这些建议可能与其他实体器官移植受者有关。我们的建议包括:从移植后新发糖尿病到移植后糖尿病(PTDM)的术语修订,从PTDM诊断中排除短暂的移植后高血糖症,扩展筛查策略(包括餐后血糖和HbA 1c)以及根据最近的临床证据对药物治疗进行基于意见的指导。会议讨论了该领域今后的研究工作,目的是建立协作工作组,解决尚未解决的问题。这些建议是基于意见的,旨在作为计划指南更新的模板,基于系统和分级的文献综述,关于PTDM的诊断和管理。
A consensus meeting was held in Vienna on September 8–9, 2013, to discuss diagnostic and therapeutic challenges surrounding development of diabetes mellitus after transplantation. The International Expert Panel comprised 24 transplant nephrologists, surgeons, diabetologists and clinical scientists, which met with the aim to review previous guidelines in light of emerging clinical data and research. Recommendations from the consensus discussions are provided in this article. Although the meeting was kidney-centric, reflecting the expertise present, these recommendations are likely to be relevant to other solid organ transplant recipients. Our recommendations include: terminology revision from new-onset diabetes after transplantation to posttransplantation diabetes mellitus (PTDM), exclusion of transient posttransplant hyperglycemia from PTDM diagnosis, expansion of screening strategies (incorporating postprandial glucose and HbA1c) and opinion-based guidance regarding pharmacological therapy in light of recent clinical evidence. Future research in the field was discussed with the aim of establishing collaborative working groups to address unresolved questions. These recommendations are opinion-based and intended to serve as a template for planned guidelines update, based on systematic and graded literature review, on the diagnosis and management of PTDM.
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